Post-Doctoral Research Visit personalized models of myopic development

Post-Doctoral Research Visit F/M personalized models of myopic development

Fonction : Post-Doctorant

The Inria Saclay Research Centre was established in 2008. It has developed as part of the Saclay site in partnership with Paris-Saclay University and with the Institut Polytechnique de Paris
.

The centre has 40
project teams
, 27 of which operate jointly with Paris-Saclay University and the Institut Polytechnique de Paris;
Its activities occupy over 600 people, scientists and research and innovation support staff, including 44 different national

Within the framework of the premyom project, we work in close collaboration with Rostchild AP-HP hospital and Essilor Luxxotica company to develop biomechanical models (using available finite element codes) of the full eye to understand the difference between normal and myopic eyes.

We have already started, in an on-going PhD project, to implement models of the different sub-parts of the eyes needed to predict its motion (cornea, sclera, muscle, optic nerve, and so on) on an existing geometry of a normal adult eye. Through this project, we aim now at using patient-specific geometries, from normal and myopic children’s eyes, from normal and myopic children’s eyes.

With the help of Jean-Marc Allain, the recruited person will process MRI and OCT images of volunteers from a cohort at Rotschild AP-HP hospital. These volunteers will do high resolution MRI images at rest, and lower resolution images of turned eyes (looking to the left and the right). These images will be completed by OCT images, which give higher resolutions on some regions of the sclera or of the retina.

We would like to have a pipeline to extract the different regions of the eyes (muscle, sclera…), and obtain meshes which can be assembled to be used in our model of biomechanical motions. To do so, developments are required to create an automatized pipe-line of feature extractions and meshing, and to couple them with the biomechanical model

Main activities (5 maximum) :

• Develop programs for segmentation of MRI and OCT images
• Prepare meshes of the eye based on these images
• Combine these meshes with mechanical models of the eye
• Publish and present the results of the work

Additional activities (3 maximum) :

• Manage the medical data in accordance with the regulation

Examples of activities:

• Analyse the requirements of {partners, clients, users}

Technical skills and level required :

• Advanced image processing (MRI & Optical images)
• Advanced Finite Element methods

Languages :
English needed, french is suggested

Relational skills :
Habit in interdisciplinary work

Other valued appreciated :
Autonomy and rigor

• Partial reimbursement of public transport costs
• Leave: 7 weeks of annual leave + 10 extra days off due to RTT (statutory reduction in working hours) + possibility of exceptional leave (sick children, moving home, etc.)
• Possibility of teleworking and flexible organization of working hours
• Professional equipment available (videoconferencing, loan of computer equipment, etc.)
• Social, cultural and sports events and activities
• Access to vocational training
• Social security coverage

Monthly gross salary : 2 788 euros/month

The candidate will have a fair understanding of image processing, and of numerical methods. He/She will be at ease with computational pipelines, and also will have an interest for interacting with clinical and industrial collaborators.