Senior Infrastructure Specialist

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

The Senior Infrastructure Specialist is responsible for planning, designing, and executing enterprise infrastructure modernization initiatives, including large-scale migrations from legacy on-premises environments to Azure Local and hybrid Azure cloud platforms. This role works in close partnership with engineering, architecture, application, operations, and cybersecurity teams to deliver secure, scalable, and resilient infrastructure solutions.

The ideal candidate brings deep hands-on technical expertise across VMware, Microsoft Azure, Azure Local, core server platforms, and automation, with a proven track record of delivering complex data center and enterprise migrations that achieve measurable improvements in performance, reliability, scalability, and cost optimization.

This role requires strong engineering judgment, the ability to execute technically complex work end-to-end, and comfort operating in highly regulated, large-scale enterprise environments.

The Senior Infrastructure Engineer plays a critical role in modernizing McKesson’s infrastructure, accelerating cloud adoption, improving platform reliability, reducing technical debt, and delivering tangible business value across the organization.

• Plan, design, and implement migration initiatives across on-premises, hybrid, and Azure cloud environments.

• Architect scalable, resilient, and secure infrastructure solutions aligned with McKesson enterprise standards.

• Evaluate legacy infrastructure and define modernization and migration strategies that support business objectives.

• Deliver migration plans that achieve documented performance improvements, availability enhancements, or cost savings.

• Lead the planning and execution of large-scale server and data center migrations to Azure Local and hybrid cloud environments, ensuring stability, performance, and minimal operational disruption.

• Partner with application teams to align infrastructure migrations with application architecture and deployment processes.

• Leverage Infrastructure as Code (IaC) tools with Terraform or Ansible to deliver scalable, repeatable, and governance-aligned compute environments that support enterprise reliability and compliance.

• Maintain accurate and up-to-date system documentation across on-premises, hybrid, and cloud platforms, including the creation, maintenance, and retirement of Configuration Management Database (CMDB) records, ensuring infrastructure assets, configuration items, and dependencies are properly documented to support operational integrity, lifecycle management, and audit readiness.

• Utilize and adhere to the McKesson Change Management process to plan, review, and implement changes within production and disaster recovery environments, ensuring minimal disruption and controlled risk.

• Participate in change reviews, implementation planning, and post-implementation validation to confirm changes meet technical, operational, and business requirements.

• Ensure infrastructure solutions comply with McKesson cybersecurity, compliance, and operational policies.

• Collaborate with compute, network, storage, operations, and cybersecurity teams to ensure end-to-end solution integrity and operational readiness.

• Act as a post-migration escalation point for complex infrastructure issues, providing root cause analysis and remediation, while serving as a trusted technical advisor who clearly communicates recommendations, outcomes,…