Principal Clinical Scientist

What if your years of clinical trial expertise could directly shape how AI understands, evaluates, and reasons about medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows — ensuring that the clinical data powering next-generation AI systems meets the same standards expected in real-world regulatory submissions.

• Organization:
  Alignerr
• Type:
  Hourly Contract
• Location:
  
  Remote
• Commitment: 10–40 hours/week

• Design and review clinical trial protocols used to generate high-quality, regulatory-grade datasets for AI training
• Interpret and audit clinical trial results for accuracy, consistency, and alignment with regulatory standards
• Evaluate AI-generated clinical analyses for scientific soundness and compliance with FDA, EMA, or equivalent agency expectations
• Provide expert, structured feedback that directly improves how AI models reason about clinical trial data, outcomes, and evidence
• Work independently and asynchronously — fully on your own schedule

• Senior-level experience designing clinical trial protocols intended for regulatory submission
• Deep expertise interpreting clinical data for regulatory agencies such as the FDA, EMA, or equivalent
• Strong background in clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail-oriented — you hold AI outputs to the same standards you'd apply to a real submission
• Clear and confident communicator who can translate complex clinical concepts into actionable feedback

• Prior experience with data annotation, data quality review, or AI evaluation systems
• Background in pharmacovigilance, medical affairs, or clinical operations
• Familiarity with AI tools or content evaluation workflows
• Experience working across multiple therapeutic areas or regulatory jurisdictions

• Work directly on frontier AI systems that are reshaping clinical and biomedical research
• Influence how AI understands, evaluates, and applies real-world clinical evidence
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert-level work
• Collaborate with world-leading AI research teams and labs on high-impact projects
• Potential for ongoing work and contract extension as new projects launch