Postdoctoral Researcher; Dr Brown's Lab

The Brown lab is focused on developing and applying advanced bioimaging techniques including live imaging methods to diverse biological problems. The project will involve studies to understand the role of paxillin phosphorylation in regulating cell migration. The focus will be on developing advanced bioimaging technologies in collaboration with graduate students in the laboratory for these studies including:
1) development of live imaging protocols for lattice light sheet microscopy and 3D image analysis to understand how membrane dynamics and cell shape are regulated by paxillin phosphorylation,
2) development of live cell imaging protocols for Stimulated Emission Depletion (STED) microscopy including halo-tagged plasmid development and
3) support for expansion microscopy methods combined with STED microscopy of fixed samples to explore the nanoscale organization of cell matrix adhesions. With a strong focus on interdisciplinary work, the position will involve working on independent research projects and providing supervision support for undergraduate and graduate students working in the Brown lab. McGill is ranked among the finest research-intensive universities in the world.

The position will involve collaboration with the Advanced Bio Imaging Facility (ABIF) of McGill University and their expert imaging scientists. The technical capabilities include widefield and confocal microscopy as well as advanced imaging such as live cell imaging, total internal reflection fluorescence (TIRF) microscopy, FLIM, STED, lattice light sheet microscopy, fluorescence correlation spectroscopy (FCS), image processing and analysis and spectral imaging.

More information about the ABIF can be found at:

EDUCATION/EXPERIENCE Required

• 1. PhD in preferred areas including Biophysics, Cell Biology, Cancer Biology, Bioengineering.
• 2. Microscopy Experience with widefield and confocal laser scanning microscopy.
• 3. Image analysis experience.
• 4. Cell culture, molecular biology, live cell imaging.
• 5. Ability to manage a diverse set of obligations on a daily basis with rapidly changing demands and priorities.
• 6. Strong interpersonal skills.
• 7. Ability to work independently and efficiently but also work well as a part of a team.
• 8. Strong verbal and written communication in English.

Would be an Asset

• 1. Some microscopy experience with lattice light sheet microscopy, STED and ExM.
• 2. Immunofluorescence labelling techniques.
• 3. Familiarity with imaging software: FIJI/ImageJ, Imaris, LASAF, ZEN, OMERO.
• 4. Experience working in a dynamic environment.
• 5. Strong verbal and written communication in French would be an asset.

Annual Salary: $60,000

Before applying, please note that to work at McGill University, you must be both authorized to work in Canada and willing to work in the province of Quebec at the campus where the position is based / located.

McGill University is an English-language university where most teaching and research activities are conducted in the English language, thereby requiring English communication both verbally and in writing.

Annual Salary: $60,000.00

Hours per Week: 35 (Full time)

Location:

Life Sciences Bldg . Supervisor:
Professor (Research)

Position

Start Date:

Position End Date:

Final date to receive applications:

McGill University hires on the basis of merit and is strongly committed to equity and diversity within its community. We welcome applications from racialized persons/visible minorities, women, Indigenous persons, persons with disabilities, ethnic minorities, and persons of minority sexual orientations and gender identities, as well as from all qualified candidates with the skills and knowledge to productively engage with…