Senior Director, Commercial Analytics & Operations Rare Disease

Senior Director, Commercial Analytics & Operations (USA Rare Disease)

Alfasigma is a privately held global healthcare company founded over 75 years ago in Italy, where it remains headquartered today in Bologna and Milan. The Group operates in over 100 markets spanning Europe, North and South America, Asia, and Africa.

Over three years ago, we embarked on a transformative journey to become a truly global innovative healthcare company with a leading focus on Gastrointestinal (GI) health
. We have experienced remarkable growth, nearly doubled our revenues, expanding geographically, and integrating several key acquisitions. We have also evolved our portfolio, expanded into rare and specialty segments, and strengthened our pipeline and people’s capabilities.

But our journey is far from complete! In fact, this is just the beginning of a bold new chapter in Alfasigma’s history. We are committed to advancing innovation and leveraging our deep expertise to provide better health and a better quality of life for patients and consumers worldwide and expand our reach across diverse markets.

As we continue to grow, we are seeking a Senior Director, Commercial Analytics & Operations
, to join the USA Rare Disease team (Intercept Pharmaceuticals subsidiary).

Scope of the role:

The Senior Director, Commercial Analytics & Operations, serves as a strategic commercial leader responsible for defining and executing the field force effectiveness strategy for a rare disease portfolio. This role oversees customer targeting and segmentation, sales force sizing and deployment, territory alignment, incentive compensation, commercial performance analytics, and launch readiness initiatives.

The Senior Director partners closely with Commercial Leadership, Marketing, Market Access, Finance, Human Resources, Medical Affairs, Data & Analytics Providers, and Executive Management to optimize resource allocation, maximize field force productivity, and accelerate business performance. This role is critical in ensuring that commercial investments are aligned with corporate strategy and that field teams are equipped with the insights, tools, and incentives necessary to achieve organizational objectives in highly specialized rare disease markets.

This scope aligns with commercial operations activities documented internally for launch readiness, field force sizing, targeting and alignment, incentive compensation, and sales force effectiveness. The Senior Director will manage internal staff, contractors, consultants, and external vendors, as well as oversee significant commercial operations budgets and strategic investments.

• Serve as a key member of the Analytics and Operations Team, influencing strategic decisions related to deployment, investment prioritization, customer engagement, and growth
• Translate corporate, brand, and launch objectives into scalable commercial operations programs
• Lead and maintain a high‑performing team focused on operational excellence, analytics, and continuous improvement
• Establish operational frameworks and cadence that ensure transparency, accountability, and alignment across commercial functions

• Own enterprise‑wide customer segmentation and targeting strategies across healthcare providers, institutional accounts, and payer networks
• Lead development of data‑driven methodologies to prioritize customers based on market opportunity, patient flow dynamics, prescribing behavior, and treatment adoption potential
• Establish targeting governance, refresh processes, and performance measurement frameworks
• Partner with Sales, Marketing, and Market Access leadership to optimize customer engagement models and call planning strategies
• Ensure…