Sr. Technical Accounting Manager

DNAnexus is the enterprise platform for precision health. We are on a mission to accelerate the development, approval and delivery of personalized treatments.

Building on 15 years of bioinformatics innovation and genomics expertise, DNAnexus provides the cloud platform that centralizes and enriches multimodal omics data, supports an extensive suite of informatics use cases, and allows secure collaboration across the care continuum. DNAnexus powers a connected ecosystem trusted by the world’s precision health leaders. This flexible ecosystem makes omics and real-world data accessible, actionable, and secure, while unlocking insights that improve patient lives.

For more information visit  or follow @DNAnexus on social media.

As we pursue these goals, it remains essential to us that we stay grounded in our values and adhere to the highest standards. At DNAnexus, you will be joining an ambitious, supportive, and driven team with diverse backgrounds but a shared passion to deliver on our mission to make personalized medicine a reality for all.

About the Role

We're seeking a Senior Technical Accounting Manager to play a pivotal role in advancing DNAnexus' accounting function. Reporting directly to the VP, Finance & Accounting, you'll drive technical accounting excellence while building the infrastructure needed to support our continued growth.

As a key member of our finance team, you'll lead technical accounting research and establish robust policies and procedures that ensure compliance with U.S. GAAP. You'll oversee both internal and external reporting processes and provide critical support during annual audits. Beyond technical responsibilities, you'll work operationally across the organization—partnering with cross-functional teams to design and implement scalable processes that enable accurate, timely accounting and reporting.

This position demands deep technical accounting expertise, strong business judgment, and excellent collaborative skills. You thrive in fast-paced, high-growth environments and can balance technical rigor with practical execution.

• Lead technical accounting research and application across key areas including ASC 606 (revenue recognition) and other complex or judgmental estimates
• Prepare and review financial statements and disclosures for annual audits as a private company, with readiness to support public-company financial reporting requirements as the business evolves
• Maintain and update accounting policies and procedures to ensure ongoing alignment with evolving business operations and U.S. GAAP requirements
• Identify and implement opportunities to streamline and enhance reporting timelines, accuracy, and automation across the close and reporting process
• Partner with cross-functional teams (FP&A, Commercial, Sales Operations, Legal, BUs) in providing technical accounting guidance to operationalize business transactions and new arrangements
• Support the VP, Finance & Accounting in driving special projects and process improvement initiatives to enhance efficiency, automation, and accuracy across the Accounting function
• Serve as primary liaison with external auditors, managing audit requests and ensuring timely completion of annual audits

About You

• 10+ years of progressive audit and accounting and financial reporting experience
• Big 4 public accounting experience and SaaS/technology industry experience strongly preferred
• Active CPA license required
• Deep technical knowledge of U.S. GAAP with expertise in complex accounting areas
• Curious and forward-thinking, with a passion for sensible automation to enhance accuracy, efficiency, and decision-making within accounting processes.
• Strong business judgment and ability to balance technical rigor with practical execution
• Excellent collaborative and communication skills with ability to influence cross-functionally
• Proven track record in fast-paced, high-growth environments

Salary and Other Compensation:

The total annual cash compensation for this position is between 170,000 and 200,000 with both a base salary and annual bonus component. Factors which may affect starting pay…