Scientist, Proteomics

## Scientist, Proteomics Apply:
On-site:
Nashville, TN:
Full time:
Posted Today:
JR101860
** Job Summary
** Proteomics has emerged as a critical discipline driving contemporary drug discovery and clinical pharmacology. Once reserved as a support function to biochemistry organizations, proteomics is now an integral part of the drug discovery engine, working as a concerted discipline-team alongside pharmacology and molecular pathology within the Discovery & Translational Sciences (DTS) Division of Inotiv. We're looking for an early-career scientist who is excited by that mission and wants to grow their expertise where proteomic data makes a real difference.  

The Scientist I, Proteomics is a Master's- or PhD-level scientist who conducts targeted and global proteomic bioanalytical studies supporting drug discovery, biomarker, and translational research programs. Working under the guidance of senior proteomics staff, this role performs hands-on sample preparation, LC-MS/MS analysis, and data processing, contributes to the development and qualification of proteomic assays, and supports communication of results to Study Directors and Sponsors.

This is an excellent opportunity for an early-career scientist to grow their technical and scientific expertise within a collaborative, cross-functional drug discovery environment.
** Scientific Responsibilities*
* * Contributes proteomics expertise to cross-functional project teams within DTS, collaborating with In Vivo Pharmacology, Molecular/Cellular Pharmacology, and Investigative & Molecular Pathology to support biomarker discovery, target validation, and translational research programs.
* Supports the evaluation and implementation of new mass spectrometry-based technologies and workflows, including biomarker-based expression profiling efforts in partnership with Molecular Pathology.
* Supports communication with Study Directors and Sponsors on targeted and global proteomics bioanalytical projects, and contributes to scientific posters, publications, and presentations that showcase Inotiv's proteomics capabilities.
* Performs, and contributes to the design of, targeted and global/discovery proteomics studies under the direction of senior scientists, ensuring compliance with established best practices and SOPs.
* Executes and assists with method development and validation (GxP and non-GxP) and sample-preparation workflows (protein digestion, immunoaffinity enrichment, high-abundance protein depletion, phospho-proteomics); operates and performs routine maintenance on LC-MS/MS instrumentation, chromatography, and automation systems.
* Performs bioinformatic and statistical analysis of proteomic datasets (e.g., Skyline, Frag Pipe, Proteome Discoverer) to identify, quantify, and interpret protein and peptide biomarkers, and presents findings to the project team.
* Drafts and revises SOPs for proteomic sample preparation, LC-MS/MS methods, and data analysis; stays current with scientific literature and emerging technologies.
* Builds working knowledge of Inotiv's capabilities, particularly at the Nashville site; performs quality control checks of data, prepares data summaries and report sections, and troubleshoots method and assay issues, escalating to senior staff as appropriate.
* Shares technical knowledge with colleagues and may assist in training team members on established proteomic and mass spectrometry techniques.
* Follows GLP and SOP requirements, including timely reporting of deviations, accurate documentation, and archival of study data and samples.
* Works with study management and operations teams to keep projects on track and support customer satisfaction from initiation through completion.
* Upholds Inotiv Core Values, safety regulations, and…