Scientist, Proteomics

Job Summary Proteomics has emerged as a critical discipline driving contemporary drug discovery and clinical pharmacology. Once reserved as a support function to biochemistry organizations, proteomics is now an integral part of the drug discovery engine, working as a concerted discipline-team alongside pharmacology and molecular pathology within the Discovery & Translational Sciences (DTS) Division of Inotiv. We're looking for an early-career scientist who is excited by that mission and wants to grow their expertise where proteomic data makes a real difference.

The Scientist I, Proteomics is a Master's- or PhD-level scientist who conducts targeted and global proteomic bioanalytical studies supporting drug discovery, biomarker, and translational research programs. Working under the guidance of senior proteomics staff, this role performs hands‑on sample preparation, LC-MS/MS analysis, and data processing, contributes to the development and qualification of proteomic assays, and supports communication of results to Study Directors and Sponsors.

This is an excellent opportunity for an early‑career scientist to grow their technical and scientific expertise within a collaborative, cross‑functional drug discovery environment.

• Contributes proteomics expertise to cross-functional project teams within DTS, collaborating with In Vivo Pharmacology, Molecular/Cellular Pharmacology, and Investigative & Molecular Pathology to support biomarker discovery, target validation, and translational research programs.
• Supports the evaluation and implementation of new mass spectrometry‑based technologies and workflows, including biomarker‑based expression profiling efforts in partnership with Molecular Pathology.
• Supports communication with Study Directors and Sponsors on targeted and global proteomics bioanalytical projects, and contributes to scientific posters, publications, and presentations that showcase Inotiv's proteomics capabilities.
• Performs, and contributes to the design of, targeted and global/discovery proteomics studies under the direction of senior scientists, ensuring compliance with established best practices and SOPs.
• Executes and assists with method development and validation (GxP and non‑GxP) and sample‑preparation workflows (protein digestion, immunoaffinity enrichment, high‑abundance protein depletion, phospho‑proteomics); operates and performs routine maintenance on LC‑MS/MS instrumentation, chromatography, and automation systems.
• Performs bioinformatic and statistical analysis of proteomic datasets (e.g., Skyline, Frag Pipe, Proteome Discoverer) to identify, quantify, and interpret protein and peptide biomarkers, and presents findings to the project team.
• Drafts and revises SOPs for proteomic sample preparation, LC‑MS/MS methods, and data analysis; stays current with scientific literature and emerging technologies.
• Builds working knowledge of Inotiv's capabilities, particularly at the Nashville site; performs quality control checks of data, prepares data summaries and report sections, and troubleshoots method and assay issues, escalating to senior staff as appropriate.
• Shares technical knowledge with colleagues and may assist in training team members on established proteomic and mass spectrometry techniques.
• Follows GLP and SOP requirements, including timely reporting of deviations, accurate documentation, and archival of study data and samples.
• Works with study management and operations teams to keep projects on track and support customer satisfaction from initiation through completion.
• Upholds Inotiv Core Values, safety regulations, and confidentiality standards, and interacts professionally with clients, colleagues, and the community.