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Medicinal Chemistry Project Leader

Job in New Haven, New Haven County, Connecticut, 06540, USA
Listing for: Scorpion Therapeutics
Full Time position
Listed on 2026-10-08
Job specializations:
  • Pharmaceutical
    Pharmaceutical Science/ Research, Drug Discovery
  • Research/Development
    Pharmaceutical Science/ Research, Drug Discovery
Salary/Wage Range or Industry Benchmark: 180000 - 280000 USD Yearly USD 180000.00 280000.00 YEAR
Job Description & How to Apply Below
Role

Lead medicinal chemistry efforts for preclinical PROTAC projects, focusing on degrader-antibody conjugates, to guide programs toward clinical candidate nomination.

Responsibilities

design and synthesize PROTACs, analyze SAR and multivariate datasets, collaborate with external CROs for synthesis and data needs, and provide strategic scientific updates to leadership.

Requirements

PhD in organic or medicinal chemistry; 8+ years in pharma/biotech drug discovery; extensive experience with antibody-drug conjugates and structure-based design; strong understanding of pharmacokinetics and in vivo pharmacology; proven project leadership and cross-functional communication skills.

High Value

expertise in PROTAC technology, antibody conjugates, structure-based optimization, pharmacokinetics, and preclinical decision-making.

Work Setup

hybrid at New Haven, CT; onsite with flexible arrangements.

Consider building your career as a Medicinal Chemistry Project Leader at Scorpion Therapeutics.

We have an opening for a Medicinal Chemistry Project Leader in New Haven, CT, United States within Bio & Pharmacology & Health, Management & Operations.

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