Associate Research Scientist II

From the very beginning, we have been focusing on the science. We came together as a team of experts, committed to quality, driven by excellence, and dedicated to experimentation. Though we faced many challenges, we remained fearless in our research and rigorous in our thinking, pushing ourselves to work harder. However, what affected us the most was the enormous burden patient’s bear and the difficulties they face, which drove us to think about what’s next.

We believe it is time to accelerate and expand that transformation. At Legend Biotech, we are excited to bring clinical trials to patients in our pursuit of a cure. While we are focusing on CAR-T in multiple myeloma, we firmly believe the prospects of cellular therapy stretch beyond just one disease or indication. The spark of hope is lit. At Legend Biotech, we are using that hope to ignite the future of CAR-T cell therapy.

Role Overview:

Legend Biotech is a clinical stage biopharmaceutical company focused on the discovery and development of novel cell therapies for oncology, immunology and infectious disease indications. We are currently seeking a talented and motivated candidate to join the R&D cell biology and immunology lab at US site. The successful candidate will contribute to the company’s efforts to develop next-generation cell therapies in solid tumor malignancies.

The successful candidate will have a strong Molecular biology/Cell biology and Immunology background, and expect to work in a collaborative cross-functional team environment, perform experiments, organize and analyze results, communicate effectively and present findings in team meetings.

Major Responsibilities:

• Assist in developing T cell therapy platform, perform cell-based immunoassays, including ex-vivio antigen specific T cell isolation and expansion, Viral-vector based introduction ofTCRs / CARs into human T cells, multi-color flow cytometry, ELISA, ELISPOT assays
• Culture and characterize genetically modified human T cells and tumor cells including gene expression and cell functionalities testing
• Plan and execute in vitro functional assays with T cells according to project goals and timelines.
• Effectively communicate plans and results in both oral and written form.
• Ability to work in a highly dynamic collaborative team environment.
• Other duties as assigned

Education:

• B.S or M.S. in biomedical science field or cell biology and immunology

Experience:

• > 5 year with B.S. or 2-5 year with M.S. Industry/academic experience in Immunology/Cell Biology, preferably Immunotherapy.

Key Capabilities, Knowledge, and Skills:

• Experience with multi-color flow cytometry and data analysis (FACSDiva, Flow Jo) required.
• Experience with primary T cell-based assays preferred.
• Excellent mammalian cell/tissue culture and sterile technique required.
• Strong organizational skills and record keeping.
• Self-motivated and willing to accept temporary responsibilities outside of initial job description.
• Comfortable in a fast-paced environment and able to adjust workload based upon changing priorities.
• Excellent interpersonal, verbal and written communication skills are essential in this collaborative work environment.

Legend Biotech USA Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend’s policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

Legend Biotech USA Inc. maintains a drug-free workplace.