Clinical Research Manager

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Salary Range: $100,000 - $110,000

Job Type: Officer of Administration

Regular/Temporary: Regular

Hours per Week: 35

Position Summary: The candidate will be an integral member of the senior leadership team within the Clinical Protocol & Data Management (CPDM) Office of the Herbert Irving Comprehensive Cancer Center (HICCC). Responsibilities include coordinating the data management activities of the CPDM, providing supervision and delegation of work assignments and evaluation of the CPDM Clinical Research Coordinators (CRCs), Data Coordinators (DCs), Research Study Assistants and other staff as assigned;

creating and promoting professional development opportunities (both internally and externally) for staff; implementing processes that improve, streamline, and stimulate the work environment; continually assessing trial complexity/workload and resource allocation to ensure patient safety and clinical research excellence; ensuring and promoting positive relationships and outcomes with private industry and other external agencies. The Clinical Research Manager reports directly to the Assistant Director, Clinical Research Operations.

Subject to business needs, the role may support flexible and hybrid work arrangements. Options will be discussed during the interview process.

• Posts/justifies new and replacement positions, screens applicants.
• On-boards and trains staff (protocol, university, departmental training).
• Liaises with the HICCC HR representative for scheduling medical surveillance, JCAHO, and other HR-related functions.
• Makes appropriate salary recommendations for new and existing staff based on prior experience and conducts annual staff performance reviews (including establishing and continually monitoring FY goals).

• Monitors, directs, and supervises staff to facilitate efficient operations.
• Determines staff workloads and protocol assignments.
• Assures the subject data collected by staff is organized and submitted timely.
• Develops quality control mechanisms to ensure accurate data reporting.
• Assists with CRF development, accuracy, and implementation for investigator-initiated trials.
• Ensures staff are adequately prepared for and successfully manage all monitoring and/or auditing visits.

• Provides protocol management and research expertise by actively participating in discussions at disease teams and collaborative research meetings, ensuring operational feasibility, compliance, and strategic alignment with CPDM and Cancer Center goals.
• Leads ongoing assessment of trials within the portfolio to evaluate feasibility, accrual trends, and resource utilization; implements priority scoring and portfolio review processes to align staffing and support with institutional priorities and study performance.
• Organizes and coordinates project activities, collaborating with multidisciplinary teams—including investigators, research nurses, coordinators, and regulatory staff to ensure timely completion of study start-up, activation, and conduct.
• Represents the department at conferences and meetings, maintaining effective communication channels between clinical, research, and administrative stakeholders to promote consistent study management, issue resolution, and operational best practices.

• Prepares and reviews study budgets for submission, negotiation, and ongoing financial monitoring to ensure accuracy, compliance, and alignment with departmental standards.
• Monitors, reports, and interprets variances to approved budgets; collaborates with the Assistant Director to develop and execute action plans that address financial gaps and optimize resource utilization.
• Uses forecasting tools to project financial outcomes and proactively identify risks and opportunities; implements strategies to support financial stability and operational efficiency across assigned studies and departmental functions.

• Assists the CPDM Leadership Team in developing, implementing, and executing departmental Standard Operating Procedures (SOPs).
• Develo…