Senior Manager, Clinical Study Lead, Inflammation & Immunology

Build our future together:
At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Senior Clinical Study Lead to join our Clinical Trial Management team, accountable for the global execution of large and complex clinical trials from study design through close out. In this role, you will lead cross-functional study teams and oversee CROs and vendors, ensuring studies are delivered on time, on budget, and in accordance with ICH/GCP and Regeneron SOPs.

You will also supervise Clinical Trial Management staff and drive process improvement initiatives. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Location:

Tarrytown, NY, Warren, NJ, Cambridge, MA

Work model/flexibility:
Primarily on‑site with hybrid flexibility

Travel percentage:
Up to 25%

• Lead the cross-functional study team as the primary point of contact for assigned studies, with high independence and accountability for timelines, budget, and quality
• Provide operational input into protocol development and key study documents, including data management, monitoring, and statistical analysis plans
• Lead feasibility assessments, site evaluation and selection, investigator meetings, and patient recruitment and retention strategies
• Select, contract, and oversee CROs and third‑party vendors to ensure delivery against the scope of work
• Manage study budgets and timelines, identify risks, and escal ... issues with clear mitigation plans
• Oversee data quality, protocol deviations, and study systems such as CTMS and TMF to keep studies audit and inspection ready
• Manage study close-out activities and contribute to clinical study reports and lessons learned
• Supervise, coach, and develop Clinical Trial Management staff while driving innovation and process improvement across the department

• Bachelor’s degree and 8+ years of relevant clinical trial experience
• Extensive experience in global clinical trial operations, with knowledge of ICH/GCP and regulatory guidelines
• Line management experience and the ability to build, lead, and develop productive study teams
• Strong budget management, vendor management, and negotiation skills
• Exceptional interpersonal, communication, and influencing skills across a wide range of stakeholders

• Advanced proficiency in trial management systems (CTMS, EDC, IVRS/IWRS) and MS applications
• Awareness of relevant industry trends and experience driving process improvement

Salary Range (annually) $ - $

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases.

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• annual bonuses or other incentive plans
• equity awards
• pension or retirement benefits
• 401(k) company match
• health and wellness programs
• fitness centers
• insurance benefits (e.g. medical, dental, vision, life and disability)
• paid time off
• family support benefits

For additional information about Regeneron benefits in the U.S., please visit

For other locations, additional information will be provided during the recruitment process.

If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where…