Throughput Functional Genomics; Discovery Lead

High-Throughput Functional Genomics (Discovery) Lead

New York

We are seeking a visionary, hands‑on scientific leader to drive our high‑throughput functional genomics discovery platform. In this role, you will collaborate closely with experimental and computational teams across Neptune, manage and develop a high‑performing group of scientists and research associates, and lead the onboarding and scale‑up of next‑generation single‑cell screening technologies. You will serve as a technical authority in genomics technologies across the organization and play a central role in enabling large‑scale screening for Neptune’s discovery engine—building a unique data moat that powers rapid and continuous target identification.

The ideal candidate brings deep expertise in advanced single‑cell CRISPR screening and sequencing technologies, combined with strong people leadership, project management experience, and a demonstrated ability to deliver large‑scale projects under tight timelines. This role requires a highly collaborative, team‑oriented mindset with a focus on generating high‑quality results at speed.

• Scientific expert and team leader:
  You bring deep expertise in advanced single‑cell and CRISPR screening technologies and have a strong track record of building and mentoring high‑performing scientific teams through clear goals, execution, and guidance.
• Systems thinker and process optimizer:
  You think naturally at scale—building efficient workflows, and enabling large‑volume research while balancing scientific rigor with operational demands.
• Results‑driven:
  You thrive in fast‑paced environments with tight deadlines, excel at prioritization, and consistently deliver complex projects on time within high‑throughput settings.
• Collaborative Team‑player:
  You enjoy leading and mentoring a team of research scientists and associates, and you excel at working across experimental, computational, and operational teams to achieve shared goals.
• Adaptable learner:
  You stay current with emerging genomics technologies, apply sound judgment when adopting innovations, and can pivot strategies effectively to meet evolving organizational needs.

• Act as a key individual contributor in a highly collaborative team, providing hands‑on expertise in the lab to de‑risk new technologies and scale up robust workflows for our high‑throughput single‑cell screening platform.
• Plan, manage, and execute a large‑scale target discovery initiative focused on high‑throughput single‑cell CRISPR screening in vitro (2D and 3D) and in vivo.
• Manage multiple complex projects simultaneously, ensuring timely execution under tight deadlines.
• Lead, mentor, and manage a dedicated team of scientists and senior research associates, fostering a culture of innovation, collaboration, and scientific rigor.
• Spearhead the identification, evaluation, and implementation of cutting‑edge technologies to enhance the speed, scale, and quality of our target discovery campaigns.
• Drive the design, execution, and optimization of sophisticated screening assays and technology development projects that directly impact program objectives.
• Develop and champion the strategic vision for technology innovation within our target discovery platform, staying current with rapidly evolving scientific fields and identifying, evaluating, and implementing new methodologies.
• Oversee experimental design, protocol development, and resource allocation across the target discovery platform to ensure project milestones and scientific objectives are met.
• Effectively analyze and present data, clearly communicating research plans, progress, and timelines to the team.
• Present scientific findings, project updates, and strategic proposals to internal and external stakeholders, contributing to publications and intellectual property filings.
• Collaborate closely with the Comp Bio team to build robust screening workflows, and maintain detailed, well‑organized, and timely documentation of experiments and data.

You must have:

• PhD, MD, or MD/PhD in genomics, biomedical engineering, molecular biology, or a related field, with training in…