Associate Research Scientist

Associate Research Scientist

Columbia University in the City of New York:
Columbia University Irving Medical Center:
Vagelos College of Physicians and Surgeons:
Systems Biology

Open Date:
Oct 20, 2025

Salary Range or Pay Grade: $79,327-$79,327

Columbia University’s Department of Systems Biology is seeking a qualified candidate for a senior level research position of Associate Research Scientists (computational) in Dr. Andrea Califano’s laboratory (Use the "Apply for this Job" box below). Candidates should have outstanding scientific and postdoctoral credentials, including first-author publications in journals relevant to the field of systems biology, and conference presentations. Candidates possessing a strong computational background combined with a good understanding of molecular biology will be especially well suited to fill this position, including background in machine learning, physics, mathematics, and related sciences.

In addition, the optimal candidate will have significant experience and publications in network-based biology, including the reverse engineering and/or use of regulatory/signaling networks to elucidate the molecular determinants of specific cellular phenotypes and associated mechanisms for follow-up experimental validation.

Integration of quantitative analysis, high-throughput experimentation, and technology development is the hallmark of systems biology  such, the Associate Research Scientist will work collaboratively on multidisciplinary teams to develop or improve algorithms for the analysis of cell regulatory and signaling networks; use models to predict how the genomic and epigenomic diversity affect physiologic or pathologic phenotypes; and develop new methods and technologies for elucidating biological mechanisms at the systems level.

The Califano lab has an outstanding record of placement for its former members ranging from academic position, including department chairs, to leading positions in industry, from group leader to chief scientific officer.

A Ph.D. in one of the following disciplines: computational biology, computer science, mathematics, physics or related quantitative science is required, plus 2 to 3 years of postdoctoral research experience. A proven first-author publication track record is required to be considered for this position.

• Knowledge of standard computer languages, including R, Java, PERL, and C/C .
• Familiarity with processing large genomic data sets and with a variety of reverse engineering techniques, including optimization-based, statistical, and integrative approaches.
• Familiarity with network biology algorithms, including both network reverse engineering and analysis, as well as with the underlying biological knowledge related to transcriptional and post-translational interactions is critical to be considered for this position, as is in-depth knowledge of the foundations of machine learning and probability theory.
• Excellent communication and writing skills.
• Strong project management skills and demonstrated mentoring skills with students and postdocs.

This institution is using Interfolio’s Faculty Search to conduct this search. Applicants to this position receive a free Dossier account and can send all application materials, including confidential letters of recommendation, free of charge.

Columbia University is an Equal Opportunity Employer / Disability / Veteran

The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting.