Research Associate, Multiomics and Immune Profiling Lab; MIP

Research Associate, Multiomics and Immune Profiling Lab

New York, NY (Onsite)

Biohub is leading the new era of AI-powered biology to cure or prevent disease through its 501c3 medical research organization, with the support of the Chan Zuckerberg Initiative.

The Biohub in New York is an independent nonprofit research institute that brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine. Biohub itself supports some of the brightest, boldest engineers, data scientists, and biomedical researchers to investigate the fundamental mechanisms underlying disease and develop new technologies that will lead to actionable diagnostics and effective therapies.

We are guided by our values of scholarly excellence; disruptive innovation; hands‑on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.

Our Vision

• We pursue large scientific challenges that cannot be pursued in conventional environments
• We enable individual investigators to pursue their riskiest and most innovative ideas
• The technologies developed at Biohub facilitate research by scientists and clinicians at our home institutions and beyond

Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution.

Biohub is seeking a detail-oriented and collaborative Research Associate to support the development and operation of an Multiomics and Immune Profiling Lab (MIP Lab) situated inside Yale University (in the Biohub Yale Annex). The MIP Lab will implement high-throughput multiomics and immune profiling including multimodal single cell profiling, as well as genetics and environment perturbation experiments with readouts from single-cell genomics and high-dimensional spatial profiling.

This position is ideal for someone who is passionate about cutting‑edge molecular technologies and thrives in a team‑oriented, large‑scale project environment.

The mission of the Biohub—a collaborative effort between CZI, Yale, Columbia, and Rockefeller Universities—is to harness the human immune system for early disease detection and prevention. We are developing cutting‑edge approaches to decode immune cell trafficking and sensing, engineer immune cells, and decipher the disease sensing code of immune cells throughout the body. The MIP Lab will implement and develop cutting‑edge immune monitoring, profiling, and engineering technologies to support the mission of the Biohub and its Annex  selected candidate will join a dynamic and exciting team and this position will allow the candidate to continue to build and expand their laboratory, scientific, and cross‑disciplinary teamwork skills.

• Set up and maintain laboratory equipment and workflows for single-cell genomics and multiomics applications.
• Execute complex single-cell genomics experiments and coordinate sample processing with collaborating investigators and core facilities.
• Establish, troubleshoot, and optimize experimental pipelines and standard operating procedures for molecular and genomic technologies, including various types of omics library preparation.
• Perform quality control and preliminary computational analysis of genomic data to support experimental troubleshooting and workflow optimization.
• Maintain detailed documentation of protocols, experimental conditions, and results.
• Work closely with staff scientists, bioinformaticians, and other team members to support large-scale collaborative projects.
• Contribute to the training and mentoring of junior team members on technical procedures.
• Interacts with collaborators/PIs and their lab members to discuss and evaluate results.
• Interacts with external contacts such as staff at biotechnology and reagent companies to consult on and further develop research methods.
• Interact with EHS (environment, health, safety) officers to ensure the smooth and…