Technician B

• Job Type: Support Staff - Union
• Bargaining Unit: SSA
• Regular/Temporary:
  Regular
• End Date if Temporary:
• Hours Per Week: 35
• Standard
  
  Work Schedule:
• Building:
• Salary Range: $55,112.05-$55,112.05

The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

We are seeking a highly motivated and detail-oriented Research Technician to join a cutting‑edge research project using induced pluripotent stem cell (iPSC)-derived neurons. This position is part of an initiative at the SNF Center for Precision Psychiatry, focusing on understanding the molecular and cellular mechanisms underlying neuropsychiatric disorders. The successful candidate will contribute to the development and characterization of iPSC-derived neuronal models to study disease mechanisms and identify potential therapeutic targets.

• Maintenance of human iPSC lines, including regular quality control assays.
• Generating 2D and 3D iPSC-derived neural cultures using various protocols.
• Performing various assays to assess neuronal and glial differentiation, including immunostaining, western blotting, and qPCR.
• Assisting with high‑throughput screening of iPSC‑derived neural cells to identify molecular and functional biomarkers.
• Analyzing cellular and molecular data, including transcriptomics and proteomics, in collaboration with the research team.
• Maintaining detailed records of experimental procedures and results, including data entry into lab management systems.
• Maintaining laboratory equipment and ensuring that all research materials and reagents are stocked and up to date.
• Other duties as assigned.

• Bachelor’s degree in neuroscience, cell biology, molecular biology, or a related field or related science or equivalent combination of education, training and experience.

• Prior experience working with iPSCs and neuronal differentiation is strongly preferred.
• Familiarity with cell culture techniques and maintaining cell lines.
• Strong laboratory skills, including PCR, immunohistochemistry, Western blotting, and microscopy.
• Experience with basic molecular biology techniques and data analysis (e.g., RNA‑seq, qPCR, proteomics) is an asset.
• Demonstrated ability to follow standard operating procedures and experimental protocols with precision and attention to detail.
• Strong organizational skills and the ability to manage multiple tasks simultaneously.
• Excellent communication skills and ability to work collaboratively in a multidisciplinary team.
• Ability to adapt quickly and troubleshoot experimental challenges.

Columbia University is committed to the hiring of qualified local residents.