Imaging Science Lead Sr. Principal Scientist

Locations:
Willing to work from one of the following sites:
Tarrytown, NY Warren, NJ Cambridge, MA Boston, MA

Work closely with imaging, therapeutic area and development leads to formulate appropriate imaging biomarker strategies to inform and advance the Regeneron clinical pipeline. Lead, design and implement multimodality imaging measures as endpoints for oncology therapeutic clinical studies. Collaborate closely with Regeneron clinical teams as imaging subject matter expert to ensure optimal design and execution of imaging strategy including development of protocols, imaging manuals, imaging charters and statistical analysis plan.

Work closely with Clinical Imaging Operations and imaging CROs to ensure the flawless conduct and data integrity of study's imaging components and endpoints. Serve as Imaging Scientific Lead in clinical trials focused on qualification and utilization of novel imaging biomarkers. Lead the interaction with regulatory agencies and site ethic committees for approval of clinical imaging biomarker development studies. Design and implement novel PET, immuno-PET and other novel imaging agents/biomarkers in clinical trials.

Oversee image analysis and interpretation of results, work closely with colleagues to oversee the development of study reports and publications as appropriate. Design and implement innovative imaging translational strategies in collaboration with preclinical/clinical research teams and external partners.

• Experience in the implementation of central efficacy assessment using tumor response criteria such as RECIST 1.1, PCWG3, Lugano and IMWG in oncology clinical trials.
• Leadership experience in the application of imaging as a quantitative endpoint in clinical and preclinical studies with an oncology focus.
• A Doctorate degree in a relevant field, with 5+ years of industry and academic clinical oncology imaging experience.
• Proven excellent written/verbal communication and organization skills.
• Ability to champion imaging innovations and lead projects effectively.

• Minimum 5+ years of imaging experience in oncology drug development and clinical PET tracer development in a pharmaceutical/biotechnology setting. Level commensurate with years of experience.
• Experience in the application of imaging as a quantitative endpoint in clinical and preclinical studies.
• Experience with regulatory agencies and inspections.
• Direct experience with preclinical oncology imaging models using PET and immuno-PET imaging biomarkers.
• Strong background in oncology, biology, molecular imaging and familiar with precision medicine approaches.
• Imaging CRO oversight and implementation of quality control procedures.

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.

For additional information about Regeneron benefits in the U.S., please visit  For other locations, additional information will be provided during the…