Principal Scientist, Translational PK/PD Modeling
Job in
Village of Tarrytown, Westchester County, New York, USA
Listed on 2026-10-14
Listing for:
Regeneron Pharmaceuticals, Inc.
Full Time
position Listed on 2026-10-14
Job specializations:
-
Research/Development
Research Scientist, Data Scientist, Pharmaceutical Science/ Research
Job Description & How to Apply Below
Role:
Principal Scientist of Translational PK/PD Modeling at Regeneron, focusing on developing quantitative and mechanistic models to support target biology understanding, therapeutic modality optimization, and early clinical dose selection.
- create and implement PK/PD models for preclinical to clinical translation, guide dose predictions, support cross-disciplinary teams in designing pharmacology studies, and contribute to the strategic direction of modeling sciences.
- Ph.D. (4+ years) or M.S. (6+ years) in pharmacokinetics, pharmaceutical sciences, engineering, or applied mathematics, with proven expertise in quantitative PK/PD modeling and simulation. Industry experience and proficiency with platforms like NONMEM, Monolix, or MATLAB are essential. Knowledge of biologics (monoclonal/bispecific antibodies, gene therapy, CAR-T, siRNAs) and PBPK modeling is preferred.
High-Value: focus on biologics and emerging modalities, early-stage clinical development, and modeling to inform dose selection.
Work setup: on-site in Tarrytown, NY, four days/week.
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