Medical Director, Clinical Development, Genetics Medicine

Build our future together:
At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Medical Director, Clinical Development to join our MASH/Metabolism team, supporting genetic medicine programs from First in Human through Phase 3. In this role, you will lead cross-functional study teams to shape clinical development strategy and ensure the scientific integrity of trials, while collaborating closely with discovery scientists, translational researchers, and regulatory colleagues.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Location:

Tarrytown, NY. Work model/flexibility:
On-site four days per week. Travel percentage: 10% to relevant conferences/congresses.

• Lead cross-functional teams to craft novel clinical development strategy for genetic medicines.
• Partner with discovery and translational scientists to understand emerging genetic targets across MASH, metabolism, rare diseases, and other therapeutic areas.
• Author and finalize protocols, amendments, monitoring plans, SAPs, and regulatory submissions.
• Evaluate the benefits and risks of assigned therapeutic candidates to inform program decisions.
• Oversee trial execution, including adverse event review and ongoing monitoring of patient health and data quality.
• Ensure team compliance with FDA, EMA, ICH, and GCP guidelines.
• Conduct literature reviews to identify development opportunities from mechanistic, pharmacological, and clinical perspectives.
• Represent clinical science in communications and meetings with regulatory agencies.

• M.D. degree (M.D./Ph.D. or prior research experience preferred)
• Board Certification/Eligibility in a relevant therapeutic area (Hepatology, Gastroenterology, Endocrinology, or Nephrology preferred)
• 2-3+ years of clinical practice or industry experience preferred
• Track record of success in clinical or scientific research settings

Salary Range (annually) $ - $

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• annual bonuses or other incentive plans
• equity awards
• pension or retirement benefits
• 401(k) company match
• health and wellness programs
• fitness centers
• insurance benefits (e.g. medical, dental, vision, life and disability)
• paid time off
• family support benefits

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases.