Temporary Scientist Position - Therapeutic proteins

Position Description We are seeking a motivated and dependable temporary Scientist to support our antibody bioconjugation and cell-based assay work for approximately 6 months. You will prepare antibody-chelator conjugates and fluorescent probes, maintain cell culture lines, and perform binding/function assays that support preclinical imaging studies across Oncology, Immuno-Oncology, and other therapeutic areas. This is an excellent opportunity to gain hands-on experience with protein bioconjugation, chromatographic purification, and cell-based validation assays in a fast-paced collaborative environment.

• Bioconjugation:
  Conjugating antibodies with bifunctional chelating agents (DFO, DOTA) and fluorescent probes following established protocols
• Purification and characterization:
  Purifying conjugates using size-exclusion chromatography; characterizing products using SE-HPLC, SDS-PAGE, and UV/Vis spectroscopy
• Cell culture:
  Maintaining mammalian cell lines and preparing cells for binding and functional assays
• Cell-based assays:
  Running binding assays, internalization assays, and functional validation experiments to confirm conjugate quality.
• Quality control support:
  Performing basic QC testing (SE-HPLC, iTLC, gamma counting) to verify product quality
• Lab coordination:
  Coordinating timelines with imaging scientists and project teams; maintaining accurate electronic laboratory notebooks

• Hands-on experience with protein chemistry, bioconjugation, or biochemistry lab techniques
• Comfortable with chromatographic methods (HPLC, FPLC, or column chromatography)
• Experience maintaining mammalian cell culture and running cell-based assays
• Excel at attention to detail and following established protocols
• Thrive in a collaborative, time-sensitive environment where reliability matters
• Take pride in maintaining accurate, organized laboratory records
• Eager to learn new techniques and work independently after training
• Proficiency with data analysis software (Excel, Prism, or similar) and electronic laboratory notebook systems
• Strong communication skills and ability to work effectively in a team setting

• B.S. in Chemistry, Biochemistry, Biology, Chemical Engineering, or related field with 1-3 years of laboratory experience
• Hands-on experience with protein chemistry or bioconjugation techniques, or strong foundational lab skills with willingness to learn
• Experience with chromatographic techniques and mammalian cell culture
• Comfort working in a laboratory environment where radioactive materials are handled (radiation safety training will be provided)