Senior Manager, Health Economics and Outcomes Research – Epidemiology - Cardiovascular, Metabolic, and Rare Diseases

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Senior Manager, Epidemiology for our Health Economics and Outcomes Research team to support our Cardiovascular, Metabolic and Rare disease programs. In this role, you will generate real-world evidence that influences the development and commercialization of innovative oncology therapies while collaborating with HEOR colleagues and key collaborators.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

• Location:
  
  Sleepy Hollow, NY
• Work model/flexibility:
  On-site 4 days/week

• Generate high-quality observational research using diverse real-world data sources to support development and commercial strategies
• Evaluate and implement emerging design and analytic methods to strengthen our RWE capabilities
• Synthesize and critically assess scientific evidence for regulatory and payor submissions, press releases, and internal business needs
• Support global HTA and payor submissions with epidemiology and RWE inputs for value dossiers and reimbursement packages
• Provide technical expertise to clinical development and evidence generation, and external control arms and hybrid approaches
• Stay current with evolving regulatory and payor expectations for RWE and guide internal teams on the implications
• Participate in epidemiologic design discussions in a peer review forum
• Drive projects forward with a growth mindset, proactively identifying solutions and managing priorities

• Doctoral degree in epidemiology or a related subject area (e.g., health services research, public health), plus at least 2 years of experience across academia, pharma/biotech, or consulting
• Hands-on experience drafting technical design documents, study protocols and/or statistical analysis plans using real-world data (claims, HER, registries), with a record of peer-reviewed publications
• Excellent communication skills, with the ability to translate complex designs and findings into clear, actionable insights for diverse audiences
• Experience conducting epidemiology and RWE research in oncology, including familiarity with cardiovascular, metabolic, or rare diseases is preferred
• Experience applying advanced analytical methods to large healthcare datasets, including causal inference, bias assessment, and robust estimation is preferred
• Familiarity with global HTA and payor evidence needs, value and reimbursement strategies are preferred

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements…