Scientist, Drug Product Development and Technology; DPDT

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Scientist to join our New Technology Team within Drug Product Development & Technology. In this role, you will support and execute the evaluation of novel technologies and modalities that impact key therapeutic areas, including Regeneron genetic medicine, ophthalmology, infectious diseases, oncology, and immunology, while collaborating with cross-functional teams across research, formulation, analytics, process development, toxicology, and PK/PD.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Full-Time, Onsite 4 Days per week;

Location:

Tarrytown, NY

• Conduct R&D evaluations of innovative drug delivery technologies that address business needs and challenges across key therapeutic areas
• Assess pharmaceutical delivery technologies and systems at various development stages, and support formulation and characterization studies for new technology development
• Support the development and evaluation of drug and gene delivery technologies across modalities, including monoclonal antibodies, fusion proteins, and RNA therapeutics
• Design and support formulation, process, analytical, and device characterization studies across multiple new technology development initiatives
• Design and execute robust experiments to evaluate LNPs and RNA-based therapeutics, including formulation development, characterization, and scale-up activities
• Support evaluation of novel excipients (including viscosity-reducing agents, surfactants, and preservatives), drug delivery approaches (including sustained-release, alternative routes of administration, and high-concentration formulations), and novel drug-device combination products
• Work and collaborate in cross-functional teams to support research, formulation, analytical activities, process development, toxicology, and PK/PD studies
• Take accountability for project execution, deliverables (including study protocols and reports), and timelines
• Compile and interpret data, and communicate findings through presentations and technical reports
• Prepare data presentations and communicate results in cross-functional team meetings, department meetings, and to management

• Master’s degree with 6+ years, or Bachelor’s degree with 8+ years, of relevant experience in Pharmaceutical Sciences, Biotechnology, Biomedical Engineering, Chemical Engineering, Chemistry, Biology, or a related field
• Experience and solid understanding of biologics formulation, analytics, and process development (e.g., genetic medicine, drug delivery technologies)
• Understanding of statistical approaches and software packages for data analysis and design of experiments (DOE) for analytical method development and/or formulation development
• Strong scientific and organizational skills, with the ability to work efficiently within a team
• Demonstrated ability to think creatively, develop solutions to complex and varied problems, and deliver productive, insightful analyses and outcomes
• Strong initiative and drive to complete ambitious tasks and proactively learn new technologies
• Excellent oral and written communication skills, with demonstrated experience in scientific writing (abstracts, publications) and/or conference presentations

• Hands-on experience in biologics/genetic medicine product development, including formulation, process, and characterization fundamentals
• Consistent record of handling a variety of analytical techniques for diverse therapeutic modalities (e.g., mAbs, oligonucleotides)
• Hands-on experience with DLS, Ribogreen assay,…