Scientist, Pharmacokinetics; Onsite

The department of Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) is seeking a highly motivated bioanalytical scientist to contribute to our drug discovery and early pre-clinical development efforts.

The Scientist will be responsible for execution and troubleshooting of quantitative bioanalytical methods of small molecules, peptides, and large molecules (biologics), utilizing both LC-MS and Ligand Binding Assay (LBA) platforms to deliver high-quality data that drives our pipeline forward.

• Method Execution & Troubleshooting:
  Develop, validate, and execute robust quantitative bioanalytical methods using LC-MS/MS, Ligand Binding Assays (LBA), and/or hybrid LC-MS/LBA workflows to support discovery and early development programs.
• Data Delivery:
  Generate, analyze, and deliver high-quality bioanalytical data for PK, PD, and in vitro studies of both small and large molecule therapeutics within established timelines.
• Sample Preparation:
  Perform manual and automated sample preparation (e.g., protein precipitation, solid-phase extraction, immunocapture/affinity purification for biological matrices).
• Lab Operations & Compliance:
  Maintain laboratory equipment and ensure all operations strictly adhere to safety, internal SOPs, and regulatory guidelines.
• Automation Integration:
  Support high-throughput workflows by operating and troubleshooting robotics and automated systems.

Bachelor’s degree with 3+ years relevant laboratory experience or MS degree (1-2 years relevant experience) in analytical chemistry, pharmaceutical sciences, pharmacology, biomedical, chemical engineering or related field.

• Large Molecule & LBA
  
  Experience:
  
  Experience with Ligand Binding Assays (LBA) quantitation of large molecules/biologics.
• Teamwork & Interpersonal
  
  Skills:
  
  Demonstrated ability to collaborate effectively within high-performing, multidisciplinary scientific teams.
• Communication:
  Excellent written and verbal communication skills, with the ability to present scientific data clearly.
• Technical Proficiency:
  Proficient in Microsoft Office Suite (Excel, Word, PowerPoint) and standard laboratory software.

• Data Analysis: A basic understanding of statistical analysis and pharmacokinetic principles.
• Small Molecule & Peptide Analysis:
  Experience with liquid chromatography (LC) and mass spectrometry (MS) for the quantitative analysis of small molecules and/or peptides in biological matrices.

#eligibleforERP

#PRD

• Bioanalysis
• Biochemistry
• Biotherapeutics
• Cell Culture Techniques
• Ethical Compliance
• GMP Documentation
• Good Laboratory Practices (GLPs)
• Immunoassays
• Laboratory Instrumentation
• Laboratory Management
• Laboratory Safety
• Liquid Chromatography-Mass Spectrometry (LC-MS)
• Pharmaceutical Sciences
• Pharmacodynamics
• Pharmacokinetics
• Pharmacology
• Small Molecules

US and Puerto Rico Residents Only:

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