Cellular Biologist II

We're hiring a Cellular Biologist II to join our Oncology lab, where you'll work hands-on with patient-derived organoids to support cutting-edge research on new and more effective cancer treatments. The Cellular Biologist II works directly under the supervision of the Senior Research Scientist and alongside a team of experienced cellular biologists and cellular specialists. In this production-focused role, you will interact with an interdisciplinary team of stem cell biologists, data scientists, automation engineers, and software developers in one of the most advanced automated platforms for cell biology worldwide.

The range of duties includes, but is not limited to, project planning, developing methodologies, conducting automated procedures, modifying and updating procedures as needed, data collection and analysis, creating and revising documentation, contributing to reports and manuscripts for publications, and providing communication and instruction. You demonstrate and model effective mental concentration and visual attention. The Cellular Biologist II is expected to lead and mentor junior technical staff and departmental assistants.

The Cellular Biologist II may be required to work flexible shifts that may include evenings, weekends, and/or holidays depending on the demands of the research project and/or laboratory operations.

• Perform automated and manual cell culture and related activities.
• Set direction for workflows; serve as technical authority; resolve complex deviations; drive optimization and innovation.
• Exercise expert judgment in designing experimental or production modifications and be responsible for high-level troubleshooting.
• Handle and process primary materials such as tumor tissues and blood samples, and culture tissue‑derived organoids, fibroblasts and iPSCs.
• Work collaboratively to perform all necessary protocols for organoid derivation, fibroblast expansion, iPSC expansion and QC, and differentiations on the robotic platform(s) or manually as required.
• Contribute to molecular, phenotypic, imaging assays, and other in vitro assays such as automated drug screenings using 3D organoid systems.
• Contribute to the design and optimization of organoid co‑culture protocols to model the tumor and tissue microenvironments.
• Store and withdraw specimens from liquid nitrogen and freezers, and prepare media and reagents required for daily work.
• Work closely with laboratory operations team to ensure reagents/consumables inventory is accurately and efficiently supplied.
• Plan and monitor resources needed to operate; maintain inventory control; coordinate space and field questions.
• Participate in monitoring and tracking of resources/expenditures across projects.
• Document results; identify problems, troubleshoot, and analyze variations observed and reported in regular testing protocols.
• Lead modification, refinement, and adaptation of techniques and procedures, partnering with engineers and other staff to define and implement large‑scale improvements.
• Provide documentation and feedback via creation and modification of SOPs, filing tickets to software and automation teams, and leading inter‑ and intra‑team meetings.
• Lead the exchange of information through demonstration and instruction.
• Perform other duties as assigned.

• Experience with human/mammalian cell culture, 3D culture systems, and iPSC culture, with additional broad expertise in cell and molecular biology techniques, is required.
• Experience with liquid handling automation is preferred.
• Demonstrated ability to develop and improve biological workflows/processes, or have contributed to the development of automation/software tools.
• Demonstrated…