Senior Software Engineer - Full-stack

Join to apply for the Senior Software Engineer - Full-stack role at Opentrons Labworks Inc.

Reports to:

Engineering Manager

Direct Reports:
None

FLSA Classification:
Exempt

Location:

Hybrid in Long Island City (Queens), NY
* * Must reside in the following states: NY, NJ, or CT

Opentrons Labworks, Inc. is a disruptive life science company leveraging its integrated lab platform to supercharge the pace of innovation in research and healthcare. Through Opentrons Robotics, thousands of institutions are automating lab operations with flexible, easy-to-use liquid handling lab robots. With our own cutting edge R&D, biopharma and biotech at large can also benefit from our world‑class genome‑scale cell engineering solutions.

This full‑stack software development role focuses on end‑to‑end feature development, owning the complete implementation from frontend user experience through backend API integration. You will build production systems that directly impact thousands of laboratories globally, creating intuitive interfaces for AI‑powered protocol generation while ensuring reliability, safety, and excellent user experience.

The Sr. Software Engineer will be a key implementation partner in building and scaling Opentrons

AI, our groundbreaking platform that leverages Large Language Models to democratize laboratory automation. Working closely with the Lead ML Researcher, you will translate research concepts and product requirements into robust, user‑facing features that enable scientists worldwide to automate their laboratory workflows.

This is a hybrid position, requiring onsite presence at our Long Island City headquarters at least 3 days per week.

• Develop performant and reliable software that will enable our users to conduct scientific experiments and control our hardware
• Take primary responsibility for customer‑facing web applications built with Python, Typescript, React, HTML, and CSS
• Actively collaborate with other engineering staff, as well as design and product teams
• Design and implement complete features end‑to‑end
• Address growing feature backlog with balanced focus on both frontend user experience and backend functionality
• Integrate backend AI services with frontend interfaces, ensuring smooth real‑time communication
• Collaborate with the Lead ML Researcher, scientists, and field scientists to understand requirements and validate implementations
• Optimize application performance and user experience based on real‑world usage patterns
• Maintain code quality through testing, documentation, and adherence to best practices
• Participate in product planning and provide technical feasibility input on new features

• Bachelor’s degree in Computer Science or similar field, or equivalent certifications and experience

• 5+ years of experience developing customer‑facing web applications using Type Script and React (including state management, responsive design, and real‑time UI updates)
• Strong backend development experience with Python, frameworks such as FastAPI, RESTful API design, and databases
• Experience writing well‑tested Type Script applications
• Experience working in multidisciplinary teams and/or directly with scientists or technical end users
• Preferred:
  Experience with AI/ML‑powered applications
• Preferred:
  Experience maintaining CI/CD pipelines and deploying to cloud environments (AWS)
• Preferred:
  Contributions to or maintenance of open‑source software
• Preferred:
  Biology or laboratory experience

• Expert proficiency in React and Type Script
• Strong understanding of component architecture, state management, and performance optimization
• Experience with real‑time UI updates, responsive design, and modern CSS frameworks
• Strong proficiency in Python and backend frameworks like FastAPI
• Experience designing and implementing RESTful APIs
• Understanding of asynchronous programming, background task processing, and ORM/database design

• Proficiency with version control (Git) and collaborative development workflows
• Familiarity with cloud platforms (e.g., AWS) and deployment practices
• Knowledge of CI/CD…