Principal Operations Scientist: Histopathology

Principal Operations Scientist - Permanent
- Newark, CA

Drive scientific excellence at the intersection of histopathology, digital pathology, and translational research as a key leader in advancing breakthrough therapies.

Principal Operations Scientist - Permanent
- Newark, CA

Drive scientific excellence at the intersection of histopathology, digital pathology, and translational research as a key leader in advancing breakthrough therapies.

Proclinical is seeking a Principal Operations Scientist specializing in histopathology to join a dynamic team in Newark, CA.

The successful candidate will provide scientific and operational leadership across histopathology, translational biomarker research, digital pathology, and related project activities. This position offers an exciting opportunity to contribute to cutting‑edge advancements in gene therapy and pharmaceuticals.

• D. in Pathology, Biomedical Sciences, Biology, Bioengineering, or a related field.
• Experience in histopathology, translational biomarker research, or closely related tissue‑based translational research.
• Strong knowledge of tissue‑based assays, pathology techniques, biomarker analysis, and scientific interpretation of histopathology data.
• Demonstrated experience leading scientific projects or small cross‑functional teams through technical guidance, influence, and project coordination
• Experience with digital pathology, whole‑slide imaging, image analysis, Visiopharm, or comparable platforms.
• Expertise in immunohistochemistry (IHC), immunofluorescence (IF), multiplex imaging, or spatial biology.
• Experience supporting proposal development, study design, or other customer‑facing scientific activities.

• Provide scientific leadership across histopathology, translational biomarker, and tissue‑based research workflows, including assay development, validation, scientific interpretation, and process optimization.
• Collaborate with internal scientific teams and customers to design, plan, and monitor execution of histopathology, biomarker, and tissue‑based research programs.

• Apply digital pathology, whole‑slide imaging, image‑management platforms, and quantitative image‑analysis tools to support scientific interpretation and project execution.

• Develop, optimize, or support image‑analysis workflows using Visiopharm or comparable digital pathology platforms, as appropriate to project needs.

• Perform or oversee quantitative tissue analysis, biomarker scoring, cell phenotyping, and spatial tissue assessments as required by assigned programs.

• Coordinate scientific project execution, priorities, timelines, resource needs, and cross‑functional handoffs within the assigned scope.

• Develop, maintain, and improve SOPs, quality systems, operational controls, and scientific best practices that support consistent project delivery

• Serve as a primary scientific and technical resource for customers, collaborators, and internal stakeholders.

• Participate actively in customer project discussions, study design, technical scoping, and project‑planning conversations.

• $ - $/Annum