Research Senior Scientist, Bioanalytical

Overview

We need your talent!

Do you want to help shape the future of biopharmaceutical innovation? At Waters Corporation, one of the world’s leading technology providers of analytical tools in the life sciences and biopharma industries, we are driven by a passion for enabling scientific breakthroughs.

With more than 7,000 employees worldwide, Waters is dedicated to delivering technologies that empower scientists to produce safe, effective, and high-quality biotherapeutics.

We are seeking a highly motivated scientist to join our state-of-the-art Immerse Delaware Lab at the University of Delaware’s Science, Technology and Advanced Research (STAR) Campus. This is a unique opportunity to contribute to cutting-edge research that advances next-generation bioprocess technologies.

At Immerse Delaware, you will be part of a collaborative ecosystem of chemists, bioprocess engineers,
and data scientists
, working with access to the latest small- and large-scale bioreactors, analytical instrumentation, and bioanalytical tools. Together, we’re uncovering new trends and opportunities in bioprocess monitoring, control, and analytical characterization of biologics and novel modalities.

Our mission is to tackle the most significant challenges in the biopharmaceutical industry through partnerships across academia and industry, including dynamic collaborations with the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL), universities, and companies worldwide.

If you’re inspired by challenging, cutting-edge science and want to see your ideas translate into technologies and therapies that make a global impact — join us.

This role reports to the Global Research Organization at Waters and offers the opportunity to leverage your technical expertise, creativity, and curiosity to help bring the next generation of bioprocessing innovations to life.

The meaningful work you will do:

• Collaborate with cell culture scientists to develop advanced analytical workflows, novel sensors/probes, and predictive models to address challenges in process optimization, monitoring, and control.
• Evaluate protein stability, variants, and glycan profiles. Apply and optimize chromatographic and mass spectrometric techniques to analyze complex biological samples and troubleshoot analytical challenges.
• Design and execute PoC studies, analyze data, and support bioprocess monitoring and analytical development.
• Support the design and implementation of PAT tools for real-time bioprocess control.
• Understand customer workflows and analytical needs to inform next-generation scientific instrumentation.
• Drive new scientific concepts and provide strategic input to R&D initiatives.

• Ph.D. in Analytical Biochemistry, Biophysics, Biochemistry, or Biomedical Engineering, or
• Master’s with 3+ years, or Bachelor’s with 5+ years of relevant experience.

• Hands‑on experience in chromatography, protein characterization, and mass spectrometry (e.g., quadrupole, TOF, ion trap).
• Strong experimental design and data interpretation skills supporting upstream bioprocess development.

• Proficient in SDS-PAGE, ELISA, Western Blot, qPCR, DLS, IEF, and CE.
• Strong analytical thinking and problem‑solving ability.

• Excellent organizational, teamwork, and communication skills.
• Self‑motivated with the ability to work independently on R&D projects.

• Occasional travel to headquarters (Massachusetts) and customer sites.

• Experience in mAb upstream bioprocess development (expression, purification, production).
• Familiarity with lab automation and robotic sample‑prep systems.
• Proficiency with Waters Empower™ and Waters Connect™ software.
• Knowledge of DoE, regression modeling, PCA, and predictive analytics for process optimization.

At Waters, we know that the perfect candidate doesn’t always exist — and we recognize that many talented people hesitate to apply if they don’t meet every single requirement. If you’re excited about this opportunity and have most of the skills or experience we’re looking for, we encourage you…