Principal Scientist - Histopathology

Principal Scientist – Histopathology

Location:

Newcastle (On-site position)

Sector:
Diagnostics

Salary: £50,000–£60,000 (dependent on experience)

Our client is a global leader in health diagnostic tools and services, specialising in providing easy‑to‑use diagnostics to improve patients' lives.

They are now seeking an experienced Principal Scientist to provide expertise on technical aspects of product development and drive current and future technologies to market.

As part of an established R&D team, the Principal Scientist will provide expertise in assay design across multiple R&D projects, manage project delivery, and work cross‑departmentally with a problem‑solving mindset to ensure successful outcomes.

Alongside practical capabilities in interpretation and scoring of Immunohistochemistry slides, the role requires a strong commercial outlook toward future strategy and system development.

• Provide expert interpretation and scoring of IHC slides.
• Give clear technical feedback to R&D teams during assay and product development.
• Bring strategic input into project direction and market/customer relevance.
• Mentor, train and support junior scientists, particularly around scoring and slide interpretation.
• Work closely with internal stakeholders, including R&D, Quality, Regulatory and Medical Scientific Affairs.

• Strong hands‑on immunohistochemistry experience, particularly IHC slide scoring and interpretation.
• Industry experience within assay development, product development, antibody development, diagnostics, medical devices or a regulated development environment.
• Knowledge of regulatory requirements such as ISO standards, IVDR, FDA and BSI.
• Prior experience operating at Principal Scientist level, bringing strategic oversight, wider market awareness and technical direction.
• Strong documentation, process adherence and ability to work in a development‑led rather than purely research‑led lab environment.

• Digital pathology experience.
• Exposure to AI algorithms within digital pathology.
• Experience with HALO or similar digital pathology/image analysis software.

This is a permanent position with a competitive salary, benefits and bonus package, offering the opportunity to work within a dynamic R&D team supporting projects with real‑life impact.