Senior Director Process Engineering & Packaging

Join AstraZeneca Biologics as a Process Engineering & Packaging Leader and drive innovation in biopharmaceutical process development and technology transfer across our UK and EU operations. This function develops early and late-stage clinical fill/finish processes, combination product assembly processes, and packaging for biopharmaceutical products in the AstraZeneca Biologics portfolio. This pivotal role offers the opportunity to lead groundbreaking process development for our diverse biologics portfolio whilst building and maintaining world-class technical capabilities!

You will lead a high-impact team of scientists and engineers, bringing scientific rigour, practical innovation, and deep collaboration to sophisticated challenges. How will you elevate design for manufacturability, technology transfer, and packaging readiness to enable seamless scale-up across a global network? Join a supportive community that values kindness alongside ambition, where taking ownership and driving outcomes are part of daily practice.

Accountabilities:
Accountabilities include leadership of the UK/EU based team responsible for process development and packaging for clinical products, development of robust drug product and device assembly processes for commercial production (in collaboration with Operations), technology transfer to both internal and outsourced commercial manufacturing, leading a sophisticated scale-down fill/finish development lab and technical support of clinical and commercial production. You incumbent oversee the process development of diverse group biopharmaceutical dosage forms, including liquid and lyophilized formulations, various primary container formats, novel drug delivery formulations (e.g. nanoparticles, high concentration formulations, etc.),

drug delivery devices and packaging. The leader must maintain a strong technical culture and be able to establish strong working relationships at internal and external interfaces. This position requires effective collaborative interactions with AstraZeneca Biologics / AstraZeneca leaders, particularly with the Global Biological Operations (Commercial Operations) organization and internal/external manufacturing sites within the manufacturing network. Experience working with functions such as late-stage formulation development, device development, clinical operations, supply chain, quality and regulatory are also essential.

You will be able to effectively lead in a matrix environment and influence broadly internally and externally.

• Provide technical and strategic leadership and management for the development of drug product and device assembly processes. Scope includes accountability for design for manufacturability, development and technical support of clinical and commercial fill‑finish processes, clinical packaging development and support of commercial packaging, technology transfer to internal and external manufacturing sites, and ad‑hoc technical support for commercial products, as needed.
• Apply scientific and engineering knowledge and tools to issues and problems arising during development and execution of manufacturing processes
• Lead and manage a technical team of 8‑10 scientists and engineers, including resource management, prioritisation, critical assessment of technical work, support of project teams, and developing relationships with functional partners
• Lead, mentor and develop high‑performing teams whilst building the next generation of technical leaders
• Provide leadership and create strategies to evolve the capabilities of the organization in alignment with AstraZeneca Biologics strategies, growing health authority expectations, and changing external drug product competitive landscape
• Drive a culture of innovation and high‑quality science and engineering
• Influence regulatory strategies and provide guidance and reviews of regulatory information packages and filings/submissions
• Challenge the status quo, yet build strong relationships with other leaders and functional partners
• Broadly influence and educate senior leaders and the larger AstraZeneca Biologics functional areas and product teams on drug product development
• Create…