Research Fellow

Job Summary

Applications are invited for a Research Fellow to work on a Medical Research Council‑funded project investigating the role of the ERG transcription factor as a master regulator of lymphatic identity and immune functionality. You will be part of an unique partnership between the University of Nottingham and Imperial College London, and will have the opportunity to collaborate with experts at City St. George’s,

University of London.

You will employ in vivo models with state‑of‑the‑art molecular and cellular assays to uncover how ERG operates as an "immune gatekeeper" during both steady‑state and inflammatory challenges. Ultimately, your findings will define a new roadmap for therapeutic targets to treat debilitating conditions such as primary lymphoedema, directly bridging the gap between fundamental molecular science and patient benefit.

Salary: £31,387 to £46,485 per annum, depending on skills and experience (minimum £35,608 with relevant PhD).

Area:
Translational Medical Sciences

Location:

UK Other

Closing Date:
Wednesday 03 June 2026

Reference: MED
1212226

• Lead investigations into how ERG regulates lymphatic identity and immune cell trafficking.
• Perform in vivo functional assays to quantify lymphatic drainage and immune cell trafficking.
• Utilize single‑cell transcriptomics and high‑resolution multiplexed imaging to map cellular landscapes in mouse and human tissues.
• Conduct mechanistic studies to identify the role of ERG in lymph node maintenance.
• Develop advanced analytical skills and benefit from a dynamic and collaborative research environment.

• Highly motivated and self‑driven with a PhD in vascular biology, immunology, or cell biology.
• Considerable experience in in‑vivo immune and vascular techniques using genetically modified mice.
• Proficiency in high‑resolution imaging and single‑cell transcriptomics (scRNA‑seq).
• Strong analytical and computational abilities to interpret high‑dimensional datasets, identify unique gene signatures, and predict cellular interactions.
• Demonstrated ability to work independently within a collaborative research group environment.

• This fixed‑term contract is for 36 months, with 36.25 hours per week. Part‑time work (minimum 29 hours per week) and job‑share arrangements may be considered.
• The position offers training, continued support, and opportunities for career progression.
• The role is part of a friendly, diverse, and supportive research group based in the Biodiscovery Institute.
• We welcome applications from the UK, Europe, and worldwide and will provide support to facilitate relocation to the UK.

We welcome applications from people of all different cultures, ethnicities, and beliefs. Our university is a supportive, inclusive, caring and positive community. We are proud to be a Disability Confident Employer (Level 2) and we have achieved an Athena Swan Gold Award. We welcome applications from the UK, Europe, and worldwide and aim to make your move to the UK as smooth as possible.