Staff Scientist - Gastroenterology; Hepatology

Location

SAINT LOUIS, MO 63110

Scheduled Hours 40

The Schwartz Laboratory in the Division of Gastroenterology, Department of Medicine, at WashU Medicine in St. Louis is seeking motivated and creative scientists to join our interdisciplinary research program investigating the biology of hepatitis B virus (HBV) and the mechanisms that allow the virus to establish and maintain chronic infection.

Our long-term goal is to understand the complex interactions between HBV and its host that drive viral persistence and to use these insights to identify new strategies toward a functional cure for chronic hepatitis B, which remains a major global health challenge and an important cause of liver related morbidity and mortality.

Our laboratory has a strong history of developing innovative human models of viral infection. We were among the first groups to establish hepatitis B and hepatitis C virus infection models using stem cell-derived hepatocytes, and we have continued to combine these systems with primary human hepatocytes, CRISPR/Cas9 gene editing, and genetically distinct HBV clones to dissect the host and viral factors that determine infection and persistence.

Recent work from the laboratory, published in Cell, identified a nucleosome-level molecular switch that primes and influences HBV infection (10.1016/j.cell.).

Primary

Duties & Responsibilities:

Following instructions and discussions with the principal investigator, designs research protocols, including developing procedures for the collection, verification and management of data.

Assists with grant preparation and reporting.

Performs complex statistical analysis of data collected and writes interpretative reports.

Verifies the correctness of the data submitted and makes recommendations based on these analyses.

Documents research topics and prepares and submits papers based on research work to publications and committees for publication or presentation to peers.

Solves practical problems relating to difficulties with equipment or test subjects.

Suggests technical or procedural improvements in testing methods.

Conducts literature searches related to research project.

Performs other duties as assigned.

All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

• Education:
  
  Master’s degree or combination of education and/or experience may substitute for minimum education.
• Certifications/Professional Licenses:
  No specific certification/professional license is required for this position.
• Work Experience:
  
  Laboratory Operations (3 Years)
• Skills:
  
  Not Applicable
• Driver's License: A driver's license is not required for this position.

• Education:
  
  Ph.D.
• Certifications/Professional Licenses:
  No additional certification/professional licenses unless stated elsewhere in the job posting.
• Work Experience:
  
  No additional work experience unless stated elsewhere in the job posting.
• Skills:
  
  Analytical Problem Solving, Communication, Computer Literacy, Data Analysis, Data Interpretations

$48,000.00 - $86,900.00 / Annually

The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

If you are unable to use our online application system and would like an accommodation, please email Candidate Questions or call the dedicated accommodation inquiry number at  and leave a voicemail with the nature of your request.

All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination,…