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Scientist, Analytical Operations

Job in Oceanside, San Diego County, California, 92058, USA
Listing for: Gilead Sciences, Inc.
Full Time position
Listed on 2025-12-20
Job specializations:
  • Security
    Data Security
Job Description & How to Apply Below
* BS with +6 years of relevant experience in Analytical Chemistry, Glycobiology, Biochemistry, Biophysics, or related field
** OR
* ** MS with +4 years of relevant experience in Analytical Chemistry, Glycobiology, Biochemistry, Biophysics, or related field
** OR
* ** PhD with 0 years of relevant experience in Analytical Chemistry, Glycobiology, Biochemistry, Biophysics, or related field.
* Hands-on experience with LC‑MS or MS/MS for glycan or glycoprotein structural characterization.
* Strong analytical reasoning and the ability to interpret complex structure–function relationships.
* Excellent communication skills and ability to work effectively in a cross-functional, matrixed environment.
* Deep expertise in glycan structural elucidation (MS/MS fragmentation, linkage analysis, exoglycosidase workflows).
* Experience linking glycan features to biological activity:
FcγR binding, effector function modulation, CH2/HOS stability, aggregation, or PK.
* Proficiency with intact/subunit MS, peptide mapping, CE-SDS, SEC-MALS, cIEF and UPLC/HPLC techniques.
* Knowledge of therapeutic antibody glycosylation, Fc engineering strategies, and effector-function silencing frameworks.
* Familiarity with ICH Q5E/Q6B and analytical method qualification for glycan assays.
* Experience with MS analysis tools (Protein Metrics, Peaks etc.) and analytics platforms (JMP etc.).
* Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way they manage their teams.
* Develop Talent - understand the skills, experience, aspirations and potential of their employees and coach them on current performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop and realize their purpose.
* Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives, and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem.

Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans .
For additional benefits information, visit:
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