Chief of Staff

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At Apheris, we are building the future of how AI is applied in pharmaceutical R&D. Our federated computing technology enables global pharma companies to collaborate securely on large AI models that accelerate drug discovery, without ever sharing their proprietary data. By powering multi‑partner data networks across small molecules, antibodies, and protein folding, Apheris is redefining how science and AI intersect. We currently host two flagship networks: the AI Structural Biology (AISB) Network, focused on protein co‑folding and binding affinity prediction, and the ADMET Network, focused on small‑molecule property prediction.

In addition, we have just launched Apheris Fold, an enterprise co‑folding application that enables pharma teams to deploy cutting‑edge models such as Open Fold 3 and Boltz‑2 directly within their own environments.

We are hiring a Chief of Staff to the CEO to operate at the center of Apheris. This is a hands‑on, high‑trust role with direct exposure to the CEO and full visibility into the company’s most important decisions. You will partner closely with the CEO and leadership team on board and investor matters, fundraising, company‑wide priorities, and critical cross‑functional initiatives. You will own preparation and follow‑through on leadership decisions, drive execution across teams, and ensure that strategic priorities translate into concrete outcomes.

This role requires strong judgment, structure, and the ability to move seamlessly between strategy and execution. You will operate with significant autonomy and discretion from day one. You will be expected to anticipate issues, surface trade‑offs, and keep the organization focused and moving s role is designed for someone who wants to sit at the nerve center of an ambitious AI company and materially shape how it scales from Series A to Series B and beyond.

• Enable the company leadership
  • Act as a force multiplier for the CEO by structuring priorities, preparing decisions, and ensuring rigorous follow‑through.
  • Own preparation, execution, and follow‑up of key leadership, board, and external meetings.
  • Keep cross‑functional initiatives moving, ensuring clarity, timeliness, and delivery quality.
  • Optimize the CEO’s engagement with key stakeholders, including investors, board members, and senior partners.
• Investor relations and fundraising preparation
  • Prepare investor and board materials in collaboration with company leadership.
  • Maintain consistent, data‑driven investor communications and reporting.
  • Consolidate company metrics, coordinate data‑room updates, and track fundraising deliverables.
  • Selectively work with the finance team on reporting, forecasting, and operational planning to ensure sound decision‑making.
• Strategic and analytical projects
  • Own and drive strategic initiatives, special projects, and analytical deep dives that support company priorities.
  • Conduct targeted market or competitive analyses where relevant to inform strategic discussions.
  • Collaborate across Product, Science, and Commercial teams to ensure progress on high‑impact work streams.
• Drive operational initiatives
  • Evolve the company’s operating cadence, including planning cycles, OKRs, and performance management.
  • Build and maintain lightweight documentation, dashboards, and communications that create transparency and scalability across teams.
  • Improve execution speed and organizational effectiveness through AI‑enabled systems and automation.

• Master’s or advanced degree in business, economics, engineering, life sciences, or a related analytical field, graduating in the top 10% from a top‑tier university or business school.
• 2‑4+ years of work experience in high‑performance, fast‑paced environments such as strategy consulting (e.g., MBB), venture capital, or high‑growth startups or scaleups.
• Strong analytical and problem‑solving skills, able to structure complexity and extract insights quickly.
• Exceptional execution drive, organization, and attention to detail.
• Strong proficiency in core tools, including expert‑level PowerPoint and Excel skills, ability to build…