Accounts Payable; AP Specialist IV

Job Category
:
General & Administrative - Ionis

Requisition Number
: IONIS
003833

Apply now

• Posted:
  October 27, 2025
• Full-Time

Showing 1 location

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

ACCOUNTS PAYABLE (AP) SPECIALIST IV

SUMMARY:

The Accounts Payable Specialist IV will support the Accounts Payable department, ensuring accurate and timely processing of invoices. This role includes invoice processing (3-way match and 2-way match), troubleshooting exception handling, resolving day-to-day AP issues, monitoring and ensuring AP aging reports are accurate, reconciling vendor statements, and monitoring the AP Inquiries mailbox. The AP Processor will assist in resolving integration and payment issues, audit Concur expense reports, support with Concur system inquiries, support system upgrades and implementations, and continuously seek ways to improve the efficiency of AP processes.

RESPONSIBILITIES:

• Daily invoice processing (3-way match and 2-way match) and handle complex processing, such as GMP invoices; partner with business teams to resolve issues.
• Assist in preparing weekly payment runs, ensuring timely processing.
• Monitor GR/IR (Received and Not Invoiced) reports and resolve discrepancies promptly.
• Reconcile vendor statements and monitor AP aging reports following up with suppliers on outstanding items.
• Work with suppliers on updating banking information when payments are rejected.
• Support system implementations and upgrades covering required testing scenarios.
• Audit employee expense reports weekly, ensuring compliance with T&E policy; work with employees to resolve audit issues.
• Monitor Concur unsubmitted expenses and follow up with employees as necessary.
• Assist employees with Concur inquiries, including credit card reconciliations.
• Ensure Desktop Procedures are current and provide training to new hires or team members.
• Assist with audits by providing necessary documentation in a timely manner.
• Run Excel reports and assist with ad hoc reporting requests.
• Assist with 1099 reconciliation and filing.
• Act as backup support for AP invoice processing when team members are unavailable or during workload increases.

REQUIREMENTS:

• Associate’s degree in Accounting, Finance, or a related field (or equivalent experience).
• 5+ years of experience in Accounts Payable or a similar accounting role.
• Strong understanding of AP processes and invoice processing.
• Proficiency with ERP systems (SAP and Coupa preferred). Proficiency in Concur System.
• Intermediate to advanced Microsoft Office (Excel).
• Ability to work independently and manage time…