Remote Executive Assistant

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.

The Opportunity

The Executive Assistant will provide executive, operational, and administrative support to the CHRO and CTOO. Responsibilities include managing complex schedules, coordinating meetings and travel, supporting department budgets and vendor activities, facilitating employee engagement initiatives, and partnering across the organization to ensure smooth day-to-day operations.

Responsibilities

Provide high-level administrative support to the CHRO and CTOO. Manage complex calendars, schedules, and meeting logistics across multiple stakeholders and time zones. Coordinate domestic and international travel arrangements, itineraries, and expense reporting. Prepare meeting materials, presentations, agendas, and executive communications. Anticipate executive needs, proactively manage priorities, and ensure timely follow-up on key actions. Handle highly confidential information with professionalism and discretion.

Support employee engagement and culture-building initiatives across the organization. Coordinate logistics and execution for Exchange Meetings, Anchor Weeks, employee recognition activities, leadership meetings, and company-wide events. Maintain HR-related communications, resources, and administrative processes. Coordinate vendor and contract administration activities for both Human Resources and Technical Operations, including purchase order management, invoice processing, contract routing, and maintaining related documentation within company systems.

Support department budget administration and vendor relationships.

Partner closely with the Executive Administration team to ensure seamless support across the organization. Collaborate on company events, leadership meetings, and special projects. Participate in regular onsite activities in the Cambridge office, including team meetings, employee engagement events, onboarding activities, and other key business initiatives, helping to foster a connected and collaborative workplace culture. Help foster a welcoming, professional, and collaborative workplace environment.

Required Qualifications

10+ years of Executive Assistant or senior administrative support experience, preferably supporting senior leaders. Exceptional organizational, planning, and prioritization skills. Strong written and verbal communication skills. Demonstrated ability to manage multiple priorities in a fast-paced environment. Advanced proficiency in Microsoft Office Suite. Proven ability to manage confidential and sensitive information with discretion.

Preferred Requirements

Experience in biotechnology, pharmaceutical, healthcare, or other highly regulated industries. Experience with purchase order processing, invoice management, vendor administration, and systems such as Link Squared, Workday, Concur, Net Suite, or similar business applications.…