Director, Pricing & Contracting

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA‑targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

DIRECTOR, PRICING & CONTRACTING

SUMMARY: Ionis Pharmaceuticals is building and scaling its U.S. commercial organization, and the Market Access team is expanding its capabilities to support current and future product launches. The Director, Pricing & Contracting is a critical leadership role responsible for supporting the Executive Director, Pricing & Contracting in developing, optimizing, and executing pricing and contracting strategies across all stages of the Ionis product lifecycle.

This individual will help ensure competitive positioning, maximize patient access, and enhance overall brand and enterprise value.

RESPONSIBILITIES:

• Support the development and execution of pricing and contracting strategies for pre‑launch and in‑market brands, aligned with overarching commercial goals.
• Lead the creation of clear, compelling business cases to secure Executive Leadership approval for major contracting initiatives.
• Continuously monitor market dynamics, policy changes, and competitor pricing to inform recommendations and maintain competitive advantage.
• Collaborate cross‑functionally with Sales, Marketing, Finance, Government Affairs, and other teams to refine pricing and contracting strategies and ensure optimal product commercialization and profitability.
• Support the National Account Team during key customer engagements and negotiations, representing Ionis’ pricing and contracting positions as needed.
• Provide pricing and reimbursement insights to help evaluate U.S. policy and legislative developments in partnership with Government Affairs and Policy.
• Partner with Finance to support quarterly close processes, including discount forecasting, GTN analytics, and utilization by contract segment.
• Drive continuous improvement and innovation in pricing and contracting processes, tools, and governance.
• Ensure compliance with all federal, state, and company policies related to pricing, contracting, and market access activities.

REQUIREMENTS:

• Bachelor’s degree in a quantitative or analytical field (e.g., finance, economics, accounting); MBA or CPA strongly preferred.
• Extensive experience building, leading, and executing pricing and contracting strategies within the pharmaceutical or biotechnology industry.
• Deep expertise in pricing and contracting analytics, including GTN forecasting and modeling.
• Proven experience developing contract proposals, including financial modeling, ROI assessments, and evaluation of GTN implications, along with demonstrated negotiation strategy capability.
• Strong…