Senior Principal - Oncology

Locations: GSK HQ, New Oxford Street, London, UK & Pennsylvania - Upper Providence, USA

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK

Join a talented and committed team at GSK, where your expertise will help shape the future of healthcare. In this Senior Principal role, you will lead complex projects by collaborating closely with cross‑functional teams to deliver scientific and strategic solutions. We value curious, motivated individuals who enjoy tackling challenges and driving meaningful impact. This is your chance to grow your career while contributing to GSK's mission of uniting science, technology, and talent to get ahead of disease together.

• Lead the design, execution, and interpretation of scientific and clinical strategies to advance key projects.
• Collaborate with internal teams and external partners, ensuring clear communication and effective decision making.
• Provide expert guidance to cross‑functional teams on scientific, technical, and regulatory matters.
• Drive innovation by identifying opportunities for new approaches and improved methodologies.
• Mentor and support colleagues to build capability and promote a positive team culture.
• Ensure project deliverables meet quality standards and timelines aligned with business goals.

We are seeking professionals with these required skills to help us achieve our goals:

• Advanced degree (Master’s or PhD) in a relevant scientific, technical, or clinical discipline.
• Significant experience (typically 8+ years) in the pharmaceutical or healthcare industry.
• Proven ability to lead complex scientific or clinical projects with cross‑functional teams.
• Strong communication skills with the ability to present complex information clearly.
• Demonstrated problem‑solving skills and a proactive mindset.
• Willingness to work in a hybrid model, combining on‑site presence in the United Kingdom and remote work.

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

• Experience leading large, multi‑disciplinary projects in a global environment.
• Background in developing and implementing innovative scientific strategies.
• Understanding of regulatory requirements and experience working with regulatory agencies.
• Track record of mentoring and developing team members.
• Comfortable collaborating across different cultures and disciplines.
• Passionate about fostering an inclusive environment where all voices are heard.

10th November 2026

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cut‑edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success.

We’re uniting science, technology, and talent to get ahead of disease together.

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