Director, Revenue Planning & Commercial Finance

Job Category
:
General & Administrative - Ionis

Requisition Number
: IONIS
003608

• Posted :
  October 19, 2026
• Full-Time
• On-site

Showing 1 location

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

DIRECTOR, REVENUE PLANNING & COMMERCIAL FINANCE

SUMMARY:

We are seeking a Director, Revenue Planning & Commercial Finance to provide strategic financial leadership, business partnership, and decision support across Ionis' Commercial organization. This role reports to the Executive Director, Global Product Strategy and Operations (GPSO) Finance, and serves as the finance partner responsible for revenue forecasting and commercial investment analysis, partnering closely with Commercial, Insights & Analytics, Market Access, Accounting, and Finance to support informed business decisions and drive sustainable growth.

The Director will lead the Company's revenue planning and forecasting processes, integrating demand forecasts, gross-to-net assumptions, and other key business drivers into a comprehensive financial outlook. This individual will evaluate and challenge assumptions, identify risks and opportunities, and provide actionable insights into revenue performance, commercial investments, and resource allocation decisions.

As a key finance partner to GPSO, Commercial, and Finance leadership, the Director will translate complex business dynamics into clear, executive-level insights and recommendations that support strategic decision-making, drive cross-functional alignment, and improve commercial investment effectiveness.

WORK LOCATION: onsite/hybrid – Carlsbad, CA

Revenue Forecasting & Planning

• Lead the end-to-end revenue forecasting process across commercial products, including monthly forecasts, quarterly updates, annual budgets, and support for strategic financial plans.
• Partner with Insights & Analytics, Market Access, Accounting, and Commercial stakeholders to evaluate key assumptions, risks, opportunities, pricing, and gross-to-net impacts.
• Integrate demand forecasts, gross-to-net assumptions, and commercial drivers into a comprehensive revenue outlook.
• Chal…