Senior Director, Clinical & BioPharma Operations

Do you have experience leading complex clinical operations and biopharma diagnostic programs across multiple stakeholders and geographies? Can you bring structure, adapt quickly, and make a measurable impact on how large, strategic studies are delivered?

If this sounds like you and you are driven by purpose, join SOPHiA GENETICS as our new Senior Director, Clinical and Biopharma Operations
, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide.

Enjoy the flexibility of a hybrid work schedule allowing 2 days PW home working, collaborating closely with colleagues in our Rolle, CH corporate office.

We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe.

As our Senior Director, Clinical and Biopharma Operations, you will play a pivotal role in orchestrating the end-to-end delivery of our flagship multimodal real-world evidence efforts as well as our portfolio of Biopharma diagnostics projects, in collaboration with leading biopharma partners. Working closely with Data Sciences, Tech, Biopharma, Product and Clinical teams, you will ensure seamless operational execution, robust data delivery, and pharma-grade quality across all programs.

You will lead the design and implementation of scalable study operations, site engagement approaches, and cross-functional ways of working that enable predictable, high-impact outcomes.

• Take overall operational accountability for large-scale multimodal real-world evidence efforts in collaboration with our pharma partners
• Oversee the portfolio of Biopharma Dx projects, from pilots to larger diagnostic collaborations, ensuring timelines, scope, and revenue commitments are met
• Lead, coach and develop an established global team of colleagues across Clinical and Biopharma Operations

• Design and continuously improve end-to-end study workflows, from feasibility and site selection through activation, data collection, and site closure
• Implement scalable operating models and shape how we engage with leading academic and clinical sites across our network of over 800 institutions globally
• Act as a credible, independent counterpart to pharma partners, ensuring transparent communication, alignment on expectations, and smooth governance

• Lead key operational performance metrics (e.g., site activation velocity, patient recruitment, data completeness and quality)
• Partner closely with Data Science to ensure data curation, quality checks, and analytics are tightly linked to site operations and study design

• Advanced degree in life sciences, medicine, pharmacy, or related field; additional certifications in clinical research (e.g., GCP, ACRP, PMP or equivalent) are a strong plus
• 10+ years’ experience in clinical research/clinical operations within pharma, biotech, medtech and/or CRO environments, including responsibility for end-to-end study delivery
• 5+ years in people management, with a track record of developing and coaching high-performing, early-career talent
• Demonstrated experience leading complex, multicenter and/or international clinical studies and managing diverse project portfolios simultaneously
• Ability to build strong relationships with external stakeholders (e.g., investigators, site teams, pharma partners) and internal cross-functional teams (e.g., data science, product, tech)

• Sickness and Accident coverage through Helsana
• Meal Vouchers at 90
  
  CHF PM with our partner cafeteria
• A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit/snacks
• Free parking in an easy to access location
• A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding
• As our global HQ, you’ll have direct interaction and exposure to senior leadership and our executive team locally

Starting Date: ASAP; H1 2026

Location:

Rolle, CH;
Hybrid with occasional international travel

Contract:

Full time, Permanent