Project Manager II: Late Phase Oncology; ISR​/CO Study Manager; Sponsor Dedicated​/US Remote

Project Manager II:
Late Phase Oncology; ISR/CO Study Manager (Sponsor Dedicated/ US Remote)

Syneos Health is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.

Whether you join us in a Functional Service Provider partnership or a Full‑Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.

Discover what our 29,000 employees, across 110 countries already know:

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to our Total Self culture - where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives - we’re able to create a place where everyone feels like they belong.

Are you an experienced ISR/CO Study Manager ready for a role where your expertise directly accelerates meaningful oncology research? At Syneos Health, you’ll step into a high‑visibility, sponsor‑dedicated position supporting a large portfolio of Investigator Sponsored Research (ISR) and collaborative (CO) studies. You’ll partner closely with Medical Affairs and principal investigators to drive studies to completion and support their path to publication.

This isn’t traditional project management—this is customer‑facing scientific study management at scale, where strong communication, organization, and oncology expertise truly matter.

• Manage a high volume of global ISR and collaborative studies
  , ensuring compliance, scientific integrity, and timely progression.
• Serve as the primary operational contact for principal investigators and study teams, providing ongoing support from startup through completion.
• Ensure accurate tracking of study status, milestones, documentation, and deliverables across the ISR/CO portfolio.
• Partner with Medical Affairs to facilitate study progress
  , troubleshoot issues, and remove barriers to execution.
• Support investigators through the publication process
  , including data requests, review timelines, and coordination with internal stakeholders.

• Oversee study budgets, financial tracking, and forecasting for assigned ISR/CO programs.
• Monitor potential risks related to funding, operations, timelines, and compliance; escalate and mitigate proactively.
• Review and approve site/vendor invoices and support client billing with accuracy and accountability.

• Represent Syneos Health as a key point of contact in this high‑visibility, customer‑facing role
  .
• Build strong working relationships with Medical Affairs, sponsors, and investigators to ensure alignment and clarity of expectations.
• Lead internal/external meetings with confidence‑driving communication, organization, and follow‑through.

• Participate in protocol‑specific onboarding and study‑related training.
• Continue to deepen your expertise in oncology and late‑phase research.
• Share knowledge and best practices with peers and cross‑functional teams to elevate study execution standards.

• MUST HAVE: Prior experience managing ISR/CO studies within a pharmaceutical or…