Technical R&D – Analytical Project Lead

Technical R&D – Analytical Project Lead

12‑month contract (possible extension) based in Basel, Switzerland. One day a week home office possible.

The role lies within analytical development for synthetic molecules, where techniques such as high‑performance liquid chromatography, gas/ion chromatography and mass spectrometry are employed to develop robust analytical methods for clinical trial and commercial supply.

• Serve as the Analytical SME/analytical project lead (APL), driving development of state‑of‑the‑art analytical control packages for synthetic molecules, including direct materials, IPCs, intermediates, and crude APIs.
• Actively contribute to portfolio delivery by ensuring efficient and effective process development analytics, including adoption of modern techniques such as modeling and simulation.
• Coach technicians and junior scientists on project work and serve as central point of contact for project‑related information.
• Supervise internal laboratory activities and/or testing activities at CLOs/CDMOs.
• Collaborate cross‑functionally with key partners in research, early development, regulatory and quality to ensure seamless project execution and alignment.
• Author, review and approve critical documents and regulatory dossiers (e.g. QIMPD, NDA) while ensuring compliance with quality standards and data integrity.
• Act as a Chemistry Project Lead (CPL), leading external testing activities at CDMOs or CLOs, and contributing to hiring and coaching of new colleagues.

• Relevant working/residency permit or Swiss/EU‑Citizenship required.
• A Master’s or Ph.D. in chemistry, pharmacy or related field.
• Minimum 5 years of professional experience within analytical development of synthetic molecules drug substances.
• Strong foundation in liquid chromatography (HPLC/UHPLC) with proficiency in UV, mass spectrometry, fluorescence and charged aerosol detection.
• Solid understanding of analytical chemistry, chromatographic techniques (HPLC, GC), titrations and other physicochemical methods.
• Excellent collaboration, technical supervision and project management skills, with a structured and rigorous approach.
• Digital acumen to support digital transformation initiatives; familiarity with statistical analysis of analytical data also advantageous.
• Excellent command of English; proficiency in German considered a plus.