Senior Director, Clinical Pharmacology
Remote / Online - Candidates ideally in
New York, New York County, New York, 10261, USA
Listed on 2026-10-09
New York, New York County, New York, 10261, USA
Listing for:
Scorpion Therapeutics
Remote/Work from Home
position Listed on 2026-10-09
Job specializations:
-
Healthcare
-
Pharmaceutical
Job Description & How to Apply Below
Role:
Senior Director, Clinical Pharmacology (Translational) at Centessa Pharmaceuticals, providing strategic leadership across neuroscience drug development from early to late stages, focusing on CNS exposure, dose optimization, and translational biomarkers.
- develop and execute clinical pharmacology strategies;
- lead model-informed drug development including PK/PD and exposure-response analyses;
- oversee clinical pharmacology studies (FIH, DDI, biopharmaceutics);
- author regulatory documents and interact with health authorities;
- partner with cross-functional teams (DMPK, Clinical Development, Biomarkers, Regulatory);
- manage CROs and external vendors;
- mentor pharmacology talent.
- PhD/MD/PharmD in relevant discipline;
- 8–12+ years in biopharma with impact in translational science;
- expertise in PK, PD, modeling tools (NONMEM, Phoenix Win Nonlin, Sim Cyp);
- experience in early-to-late stage and regulatory submissions;
- strong understanding of CNS exposure and biomarkers;
- excellent communication and leadership skills.
High-value: neuroscience, CNS, translational pharmacology, biomarker integration, regulatory engagement, remote work with occasional travel.
Position Requirements
10+ Years
work experience
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