Global Medical Lead, Neurometabolic

About the Role

The Global Medical Lead (GML), Neurometabolic is the strategic and medical/scientific owner of all global medical affairs activities across the neurometabolic portfolio, leading the end-to-end global medical strategy, evidence generation plans, and lifecycle medical activities for programs spanning early development through commercialization.

As the senior medical affairs leader for the neurometabolic franchise within Global Medical Affairs, this individual drives integrated medical strategy, ensures robust cross-functional alignment, leads scientific engagement worldwide, and guides the development and implementation of medical plans across geographies.

This role acts as the central node connecting global, regional, and local medical teams, ensuring coherent execution, knowledge flow, and scientific excellence. The GML is accountable for advancing scientific understanding, supporting optimal clinical use, and improving patient outcomes across the neurometabolic disease portfolio.

The ideal candidate will bring experience across multiple stages of asset development, including both early clinical development and launch/commercialization readiness, and will demonstrate the ability to build scientific strategy in complex and evolving rare disease environments.

What You'll Do

Global Medical Strategy Leadership

• Serve as the enterprise medical lead for the Neurometabolic Franchise, responsible for global medical strategy, scientific narrative, and lifecycle medical planning.
• Develop and maintain Global Medical Plans (GMPs) and ensure alignment with integrated evidence generation plans (IEGPs).
• Partner closely with Global Asset Leadership and the Head of Global Medical Affairs to ensure medical strategy aligns with portfolio priorities and enterprise objectives.
• Define key scientific pillars, messaging platforms, evidence generation priorities, and insight-gathering strategies across all stages of development.
• Lead medical strategy development for programs ranging from early-stage clinical development through launch readiness and commercialization.
• Ensure medical plans evolve appropriately as assets advance through development milestones and lifecycle stages.

Evidence Generation & Data Strategy

• Lead the global strategy and scientific rationale for clinical, real-world evidence (RWE), health economics and outcomes research (HEOR), and observational evidence generation activities.
• Collaborate closely with Clinical Development, Biometrics, Regulatory Affairs, Value & Access, and Evidence Generation teams to ensure decision-grade evidence addresses clinical, regulatory, payer, and stakeholder needs.
• Identify evidence gaps and proactively develop plans to address unmet scientific and clinical questions.
• Oversee global data dissemination activities, including congress strategy, publications planning, scientific communications, medical education activities, and advisory boards.
• Ensure evidence generation strategy supports both current and future franchise objectives.
• Maintain awareness of evolving stakeholder expectations and emerging evidence requirements across global markets.

Scientific Leadership & External Engagement

• Serve as a primary scientific and medical spokesperson for the neurometabolic franchise.
• Represent the organization at scientific meetings, advisory boards, investigator meetings, and external collaborations.
• Lead global KOL engagement strategy and scientific advisory planning to inform medical strategy, evidence generation priorities, and lifecycle decision-making.
• Build and maintain meaningful relationships with international thought leaders, investigators, patient advocacy groups, academic partners, and…