Clinical Medical Monitor

Med X CRO
· Fully Remote
· Full-Time or Fractional

Med X CRO is a Toledo, Ohio–based contract research organization specializing exclusively in neuroscience, with a focus on neurovascular and peripheral therapies. We're a lean, agile team delivering studies globally across the U.S., Europe, and beyond. Our edge is speed, specialization, and quality: rapid trial startup and enrollment, backed by the precision of a dedicated neuroscience team.

If you're a clinical professional who wants to apply your expertise to advancing neuroscience therapies, and you thrive in a fast-moving, collaborative environment, we'd love to meet you.

As Medical Monitor, you'll provide medical and scientific oversight across our clinical studies. You'll be the clinical expert for sponsors, investigators, and internal teams. You'll safeguard subject safety, guide medical decisions, and help keep study data clinically sound from protocol design through final reporting.

This is a fully remote position. We welcome both full-time and fractional candidates, so if you're looking for a dedicated role or want to add meaningful clinical research work alongside other commitments, we'd like to hear from you.

Reports to:

Director of Clinical Affairs / COO

• Provide ongoing medical monitoring and oversight for assigned studies
• Review and assess adverse events (AEs), serious adverse events (SAEs), and device- or procedure-related events for seriousness, causality, and expectedness
• Serve as the clinical point of contact for investigators and site staff on eligibility, protocol, and safety questions
• Identify and evaluate emerging safety signals and trends; escal… as appropriate
• Support unblinding decisions and urgent safety issues, including after-hours availability as required
• Provide clinical input on protocols, amendments, informed consent forms, investigator brochures, and CRF design
• Develop and maintain Medical Monitoring Plans and safety management documentation
• Review and approve eligibility exceptions and protocol deviation assessments
• Perform ongoing medical review of clinical data, listings, and narratives for accuracy and clinical plausibility
• Write and review SAE narratives, safety reports, and the medical sections of clinical study reports (CSRs)
• Support DSMB/DMC and Clinical Events Committee (CEC) activities, including preparing materials and attending meetings

• Ensure safety reporting complies with ICH-GCP and FDA regulations (e.g., 21 CFR Parts 50, 56, 312, 803, 812) and applicable international requirements
• Support regulatory submissions, audits, and inspections
• Train investigators, site staff, and internal teams on protocol-specific medical and safety topics
• Partner with Clinical Operations, Regulatory, Biostatistics, Data Management, and sponsors to resolve medical issues efficiently

• Advanced degree in a clinical or life sciences field (e.g., MD, DO, PharmD, PhD, NP, PA, or MSN), or a BSN/RN with equivalent clinical research experience
• 2+ years of experience as a Medical Monitor or in clinical research, drug/device safety, or clinical development (CRO, sponsor, or academic setting)
• Strong working knowledge of ICH-GCP, FDA regulations, and safety reporting requirements
• Experience evaluating AEs/SAEs and reviewing clinical trial data
• Excellent written and verbal communication skills, including with investigators and sponsors
• Ability to manage multiple studies and priorities in a fast-paced CRO environment

• Neuroscience experience, clinical and/or research (e.g., neurology, neurosurgery, neurocritical care, stroke, or interventional neuroradiology)
• Experience with neurovascular or peripheral vascular studies
• Familiarity with EDC and…