Proposal Strategy and Operations Manager San Francisco, Remote

At Picnic Health , we're building the future of non-interventional clinical research, powered by AI and centered on patients. Our mission is to make it radically easier, faster, and more affordable to generate high-quality real-world evidence. We're replacing the legacy, services-heavy model with a modern, AI-first approach that unlocks insights from rich, multi-modal data—from clinical notes and imaging to lab results— engaging patients directly through our personal health assistant , Picnic

AI, which meets them where they’re at and delights them along the way (with an industry leading NPS of 76), patients participate actively in the research they care about.

Picnic Health is already a trusted partner to 7 of the top 10 pharmaceutical companies. Our work spans 40+ disease areas and has supported over 60 peer-reviewed publications, including an FDA submission that incorporates Picnic Health data.

Founded in 2014, we’ve raised $100M+ from top investors like Amplify Partners, Felicis Ventures, B Capital Group, and Y Combinator. Our business running non-interventional studies more than doubled last year, and we’re growing even faster in 2025. We’re a team of doctors, patients, data nerds, engineers, and builders, reimagining how clinical research works — and we’re just getting started!

The Opportunity

As the Proposal Strategy and Operations Manager, you will build a system and process that enables a cross-functional team to transform complex technical capabilities into compelling, winning proposals . This role is critical to our success in the competitive non interventional study space requiring someone who can transform complex technical capabilities into compelling, winning proposals. This is a builder role. You’ll wear multiple hats—leading proposals, creating structure where it doesn’t exist, and partnering across teams.

You won’t be doing this alone, but you will be accountable for making it happen.

At Picnic Health, AI is at the core of everything we do. We're looking for individuals who are not just comfortable with, but genuinely excited by and actively experimenting with, the power and potential of AI.

What you’ll do:

• Strategic Proposal Leadership
• Develop and execute proposal strategies that differentiate Picnic Health in competitive landscapes
• Collaborate with Sales, Scientific Solutions, Product Delivery and Operations teams to craft compelling value propositions
• Analyze RFPs and client requirements to develop winning positioning and messaging
• Proposal Management & Execution
• Leverage project management tools and processes to project manage complex, multi-stakeholder proposal processes with tight deadlines
• Coordinate cross-functional teams including Scientific Solutions, Product, Delivery and Operations, Legal, and Finance
• Ensure all proposals meet client requirements, compliance standards, and internal quality benchmarks
• Develop standardized templates, timelines, processes, and best practices to improve efficiency and win rates
• Identify, test and roll out technology and tools to build scalable processes that enable faster and more efficient proposals.
• Content Development & Optimization
• Levarge Picnic Health experts to create compelling executive summaries, technical approaches, and capability statements
• Maintain and continuously improve proposal content library and knowledge management systems leveraging process, technology and tools
• Work with solutions and design to ensure consistent messaging and branding across all proposal materials
• Win/Loss Analysis & Continuous Improvement
• Conduct thorough win/loss analyses to identify improvement opportunities
• Track proposal metrics and conversion rates to optimize processes
• Collaborate with Sales teams to understand client feedback and market dynamics
• Implement process improvements based on data-driven insights

What you’ll bring:

• 5+ years of experience leading complex RFP responses within CROs, real-world evidence vendors, or digital health companies supporting life sciences clients.”
• Proven track record of winning competitive, high-value proposals (>$1M)
• Experience with real-world evidence, clinical research, or healthcare data…