Sr Manager, RWE Analytics

Sr Manager, RWE Analytics – Plainsboro, NJ (Hybrid – 3 days onsite, 2 days work from home)

Contract length unspecified;
Pay rate unspecified.

Job Summary:

The Senior Scientist, Health Economic Resources (Sr Manager, RWE Analytics) will support the design, execution, and communication of real‑world evidence studies using claims, EHR, registry, and linked data sources. This role provides hands‑on analytics, AI/ML support, and contributes to evidence for clinical development, market access, safety, and regulatory objectives.

• Support observational study design, execution, and communication.
• Conduct hands‑on RWE analytics using claims, EHR, registries, and emerging RWD.
• Perform feasibility assessments of new data modalities (SDOH, genomics, biomarkers, clinical notes).
• Develop analytic data files, table shells, QC, programming, and statistical outputs.
• Lead or support AI/ML pilots and scale analytic frameworks.
• Partner cross‑functionally with development, commercial, market access, medical affairs, safety, and legal.
• Draft analysis reports, manuscripts, and conference presentations.
• Manage external research partners/vendors.

• PhD or Master’s in Epidemiology, Biostatistics, Public Health, or related field.
• 3+ years’ real‑world evidence and epidemiology analytics experience.
• Experience with claims, EHR, hospital billing, SEER, and linked datasets.
• Strong understanding of epidemiologic/statistical concepts (bias, confounding, incidence, regression, survival analysis, causal inference).
• Proficiency with SAS, R, Python; AI/ML experience preferred.
• Oncology experience preferred.
• Strong communication and collaboration skills.
• Ability to excel in a fast‑paced environment with tight timelines.

System One and its subsidiaries are equal opportunity employers. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.