Remote Data Engineer; Bioinformatics

Position: Remote Data Engineer (Bioinformatics)
We’re looking for a  Data Engineer with a strong background in bioinformatics and genetics  to help build the data pipelines supporting Our Future Health’s growing Clinical Research Recruitment Service.
This is an opportunity to combine  genetics, bioinformatics and modern data engineering  , working with data at significant scale while contributing directly to research that could improve how diseases are prevented, detected and treated.

Our Future Health is an ambitious collaboration between the public, charity and private sectors, designed to help people live healthier lives for longer through better prevention, earlier detection and improved treatment of diseases. We will speed up the discovery of new methods of early disease detection, and the evaluation of new diagnostic tools, to help identify and treat diseases early, when outcomes are usually better. With over 2.7M volunteers across the UK, we’re now the world’s biggest health research programme of its kind, and our volunteer group is also more diverse than other, similar health research programmes.
Technology and data are central to our mission. Our systems power web sites, clinics across the UK, secure analytics and research systems, pipelines that process highly sensitive health and genetic data, and we are continuing to grow our engineering capability to support this ambition.

Our Clinical Research Recruitment Service helps life sciences and academic organisations identify potential participants for clinical studies. As the service grows, we need to turn scientific workflows and manual processes into  robust, reusable and scalable production pipelines  .

We’re looking for a Data Engineer with a solid understanding and experience of bioinformatics, in particular tools and methods associated with genomic data. You know how to create repeatable and reusable products and can communicate to and between technical and non-technical stakeholders, with the ability to facilitate discussions and manage different perspectives within a multidisciplinary team including scientists, software engineers, product managers and other data engineers.

Support the build of re-usable data pipelines used to identify prospective clinical trial participants.
Produce logic for data transformation steps as code, which meets the requirements for our end users and builds well curated, accessible and quality controlled data for analysis.
Developing prototypes for pipelines for complex transformations drawing on existing workflows developed in industry and academia.
Keep abreast of best practice in data engineering across industry, research and Government and facilitating the adoption of standards.
Providing technical input into the upstream parts of the data pipeline, including the specification and transfer of data from data providers.
Routine ad-hoc data curation activities requiring hands on development of bespoke ETL cleaning scripts using languages such as Python.
Working with researchers to understand the data requirements and work with them to deliver the data needed for their projects.

Experience building and maintaining robust, scalable and efficient data pipelines. Capable of processing very large amounts of data based on feeds from multiple systems using a range of different technologies.
Detailed knowledge and understanding of genomic data (experience in genotyping and imputation is advantageous).
Experience using bioinformatics file standards (VCF, BGEN etc) and tools (PLINK, bcftools, QCtools etc)
Highly proficient in Python.
Docker) and deployment (e.g. Understanding of common data transformation and storage formats, e.g. Awareness of data standards such as GA4GH ( ) and FAIR ().

Experience with Spark, Databricks, data lakes.
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