Principal Clinical Database Programmer - Ecoa

When our values align, there's no limit to what we can achieve.

Join Parexel as a Principal Database Programmer – eCOA (eCOA Study Designer), a fully home-based opportunity open to candidates across the UK!

The Principal Database Programmer – eCOA (eCOA Study Designer) provides technical expertise for the design, configuration, testing, deployment and maintenance of electronic Clinical Outcome Assessment (eCOA) solutions used in clinical trials. The role translates protocol, assessment and operational requirements into compliant participant, caregiver and clinician facing questionnaires, schedules and workflows within approved eCOA technologies. The eCOA Study Designer works independently across multiple projects, collaborates with sponsors and cross-functional study teams, and supports integration of eCOA configurations with Electronic Data Capture (EDC) systems.

• Interpret protocols, schedules of assessments, eCOA specifications and licensed instrument requirements to design appropriate electronic data collection workflows.
• Configure questionnaires, screens, field properties, code lists, schedules, activities, completion settings, branching logic, rules, reminders, alerts, notifications and study settings in the approved eCOA platform.
• Apply established naming conventions and build standards, including clear identification of eCOA-specific forms, fields and code lists.
• Coordinate the initial eCOA configuration and controlled push to EDC; maintain alignment among the eCOA configuration, EDC draft and applicable CRF versions.
• Assess and implement approved protocol amendments, production revisions, translations and study maintenance changes while protecting data integrity and traceability.

• Perform technical quality control of eCOA configurations against approved specifications, including screens, questionnaire workflows, rules, notifications and schedules.
• Prepare system demonstrations, test evidence, questionnaire screenshots and other materials required for internal review and User Acceptance Testing (UAT).
• Support pre-UAT meetings, UAT execution, defect triage and resolution; ensure issues are documented in the approved study issue-tracking process.
• Coordinate deployment readiness and communicate completion of technical quality control and UAT prerequisites to applicable stakeholders.
• Support post-production troubleshooting and controlled implementation of approved corrections.

• Collaborate with Clinical Database Programming, Data Management, eCOA Clinical Data Analysis, COA Science, Clinical Operations, and other study functions to finalize eCOA requirements and resolve design issues.
• Lead or participate in recurring design and build meetings, provide configuration status, identify risks and dependencies, and elevate issues when required.
• Interact with sponsors and vendors as a technical contact for eCOA design, specification, testing and deployment topics, as assigned.
• Provide input to study timelines, monitor assigned work and communicate changes in scope, assumptions or resourcing needs.
• Provide technical advice to internal project teams and support multiple projects simultaneously.

• Create and maintain eCOA specifications, configuration records, implementation checklists, test evidence, screenshots, issue records, version documentation, and other required study artifacts.
• Maintain study documentation in accordance with SOPs, Work Instructions, and guidelines to support traceability, inspection readiness, and regulatory compliance.
• Document deviations, decisions, risks, and configuration limitations and communicate them to the appropriate project stakeholders.
• Follow system life cycle, access control, change control, validation and…