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Senior Project Manager – Oncology​/Hematology; Phase III

Remote / Online - Candidates ideally in
Hawaii, USA
Listing for: Syneos Health, Inc.
Remote/Work from Home position
Listed on 2025-12-19
Job specializations:
  • Management
    Healthcare Management
Job Description & How to Apply Below
Position: Senior Project Manager – Oncology/Hematology (Phase III)

Senior Project Manager – Oncology/Hematology (Phase III)

Updated: November 13, 2025
Location: USA-HI-Remote
Job :

Description

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.

WORK HERE MATTERS EVERYWHERE

Why Syneos Health

  • We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
  • We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
  • We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong.

Job Responsibilities

Senior Project Manager – Oncology/Hematology (Phase III)

Are you a seasoned CRO project leader passionate about advancing oncology and hematology research
? Do you thrive in a fast-paced, collaborative environment where your leadership directly impacts patient outcomes? Join our team as a Senior Project Manager and take ownership of complex Phase III trials
, driving projects from proposal through delivery and shaping the future of cancer care.

About the Role

As a Senior Project Manager, you will take a lead role in advancing Phase III Oncology and Hematology clinical trials, managing complex, global initiatives. You’ll lead and inspire cross-functional teams, mentor emerging project managers, and act as the primary strategic partner for our clients, ensuring every milestone is delivered on time, on budget, and with exceptional quality.

What You’ll Do

Project Leadership & Delivery

  • Drive the operational and financial success of Phase III clinical trials.
  • Lead cross-functional teams across Clinical Operations, Regulatory Affairs, Data Management, Biostatistics, Medical Affairs, Pharmacovigilance, and QA.
  • Act as the primary liaison with clients, ensuring smooth project launch, conduct, and closeout.
  • Oversee project deliverables, timelines, and budgets while proactively identifying and mitigating risks.
  • Mentor junior project managers and project support staff, fostering collaboration and professional growth.

Financial & Operational Accountability

  • Own project budgets, forecasts, and financial performance.
  • Ensure alignment and accountability across all vendors and study partners.
  • Implement contingency plans and risk mitigation strategies to keep projects on track.

Reporting & Communication

  • Maintain and evaluate project progress using advanced tracking tools.
  • Prepare and present project materials for internal and external stakeholders.
  • Support inspection readiness and Trial Master File compliance.

Business Development

  • Participate in bid defense meetings as the potential project lead.
  • Build strong client relationships to generate new opportunities.
  • Stay up-to-date on oncology/hematology trends and the evolving drug development landscape.

Management & Mentorship

  • Train and mentor new project managers and clinical staff.
  • Facilitate team communication, collaboration, and professional development.
Who You Are
  • Experienced Global Project Leader (NA, LATAM, EMEA, and APAC) with strong Phase III CRO project management experience and a proven track record of delivering clinical…
Position Requirements
10+ Years work experience
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