Principal Project Manager; office locations

Job Description

We are looking for a Principal Project Manager to join the Office of the Chief Technology & Product Officer (CTPO). This is an exciting opportunity to shape and deliver high-impact technology and product initiatives that support our wider mission.

You will bring clarity, structure, and momentum to complex projects, helping teams work together effectively and ensuring strong governance across a diverse portfolio.

• Manage complex projects end to end, ensuring successful delivery, by managing planning, reporting, and end-to-end risk and issue management with a structured, and consistent approach.
• Build strong, trusted relationships with senior leaders, Service Management, Product, Service Design, and suppliers to enable effective collaboration and shared outcomes.
• Provide oversight across the CTPO portfolio, strengthening governance, improving visibility, and supporting informed decision-making.
• Coordinate programme and governance boards, ensuring reporting, escalation, and updates are clear, timely, and transparent for all stakeholders.

• Experience leading complex projects in large, matrixed environments.
• A collaborative approach and the ability to build trusted relationships with senior stakeholders and executive leaders.
• A strong track record of delivering end-to-end programmes that create meaningful and lasting impact.
• Confidence in setting up and managing project governance, and risk management across complex delivery environments.
• The ability to bring structure, clarity, and calm to fast-moving and evolving portfolios.
• Strong communication skills, with the ability to turn complexity into clear and useful insight for a range of audiences.

Whilst Project Management certifications are desirable, we are mostly interested in your experience.

Salary from: £70,000

Closing date for applications - Friday 19th June

• Generous Leave: 30 days’ holiday plus bank holidays, additional leave for long service, and the option to apply for up to 30 days of remote working abroad annually (approval required).
• Family-Friendly:
  Blended working arrangements, flexible working, enhanced maternity, paternity and shared parental leave benefits.
• Pension & Financial:
  Defined contribution pension (Genomics England double-matches up to 10%, however you can contribute more if you wish), Life Assurance (3x salary), an Electric Vehicle salary sacrifice scheme and a Give As You Earn scheme.
• Learning & Development:
  Individual learning budgets, support for training and certifications, and reimbursement for one annual professional subscription (approval required).
• Recognition & Rewards:
  Employee recognition programme and referral scheme.
• Health & Wellbeing:
  Subsidised gym membership, a free Headspace account, and access to an Employee Assistance Programme, eye tests, flu jabs.

Genomics England is actively committed to providing and supporting an inclusive environment that promotes equity, diversity and inclusion best practice both within our community and in any other area where we have influence. We are proud of our diverse community where everyone can come to work and feel welcomed and treated with respect regardless of any disability, ethnicity, gender, gender identity, religion, sexual orientation, or social background.

Genomics England’s policies of non-discrimination and equity and will be applied fairly to all people, regardless of age, disability, gender identity or reassignment, marital or civil partnership status, being pregnant or recently becoming a parent, race, religion or beliefs, sex or sexual orientation, length of service, whether full or part-time or employed under a permanent or a fixed-term contract or any other relevant factor.

Genomics England does not tolerate any form of discrimination, harassment, victimisation or bullying h behaviour undermines our mission and core values and diminishes the dignity, respect and integrity of all parties. Our People policies outline our commitment to inclusivity.

We aim to remove barriers in our recruitment processes and to be flexible with our interview processes. Should you require any adjustments that may help you to fully participate in the recruitment process, we encourage you to discuss this with us.